The transfer rate of a probe molecule across the interfacial layer of a water-in-oil (w/o) microemulsion was investigated using a combination of transverse field muon spin rotation (TF-μSR), avoided level crossing muon spin resonance (ALC-μSR), and Monte Carlo simulations. Reverse microemulsions consist of nanometer-sized water droplets dispersed in an apolar solvent separated by a surfactant m...

Particles stabilize fluid interfaces. In particular, oil/water Pickering emulsions undergo limited coalescence, yielding droplets of smaller size as the amount particles is increased. Herein, we studied effect hydrophobic nanoparticles (<10 nm, alkyl-coated) on submicronic (ca 100 nm) formed in an Ouzo system. We investigated thoroughly water/tetrahydrofuran (THF)/butylated hydroxytoluene (BHT)...

BACKGROUND Aquafol, a microemulsion propofol, causes more severe and frequent pain on injection than propofol. The purpose of this study was to compare a combination of lidocaine and ketamine on aquafol-induced pain with lidocaine or ketamine alone during the induction of anesthesia. METHODS In this prospective, randomized, double-blinded study, 130 healthy patients who were undergoing electi...

In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

To improve the efficiency of the intradermal delivery of genistein and other two isoflavones (daidzein and biochanin A), we tried to clarify the usefulness of microemulsion by in vitro study on excised guinea pig dorsal skin and Yucatan micropig skin. Using microemulsion consisting of isopropyl myristate (IPM), 150 mM NaCl solution, Tween 80 and ethanol as a vehicle, the solubility of all the i...

The last two decades have witnessed an explosion of interest in the field of droplet-based microfluidics for their multifarious applications. Despite rapid innovations in strategies to generate small-scale liquid transport on these devices, the speed of motion is usually slow, the transport distance is limited, and the flow direction is not well controlled because of unwanted pinning of contact...

The bioavailability of two microemulsion formulations of cyclosporine (Drug A, cyclosporine Neoral, Sandoz Pharma Ltd., Switzerland and Drug B, cyclosporine Bioral, Panacea Biotec Ltd., India) was compared in 12 healthy volunteers in a randomized, double blind, cross over manner. Blood cyclosporine levels were analyzed by high performance liquid chromatography. The peak concentration was 1600.6...

The Lattice Boltzmann Method is used to simulate the dynamics of droplet deformation in a channel flow under various conditions. The droplet behavior has been investigated under transient conditions. For cases where the droplet remains attached to the surface, the shape deformation of the droplet during crawling is captured. It has been shown that there is a limiting value for the droplet volum...

calcium carbonate nano-particles were synthesized by a reverse micro-emulsion method at room temperature with tween® 80 and span® 80 as co-surfactants. the nano-particles synthesized were surface modified by stearic acid. an important operating variable in the span 80-tween 80/toluene/water reverse micro-emulsion system, the ω-value (water/surfactant molar ratio) was investigated. the material ...