Antibiotic resistance is a rapidly evolving problem that is not being adequately met by new antimicrobial drugs. Thus, there is a pressing need for effective antibacterial therapies that can be adapted against antibiotic-resistant bacteria. Here, we engineered synthetic bacteriophage to combat antibiotic-resistant bacteria by overexpressing proteins and attacking gene networks which are not dir...

Stable resistance to infection with Wheat streak mosaic virus (WSMV) can be evolved de novo in selfing bread wheat lines subjected to cycles of WSMV inoculation and selection of best-performing plants or tillers. To learn whether this phenomenon might be applied to evolve resistance de novo to pathogens unrelated to WSMV, we examined the responses to leaf rust of succeeding generations of the r...

Resistance levels to deltamethrin were measured in 5 natural populations of Anopheles sinensis. The median lethal concentrations (LC50S) of deltamethrin in these populations were higher than those in susceptible strains originating from the same populations, especially in the Wenzhou population, which had a resistance ratio (RR50) of 11 relative to its susceptible strain. Resistant strains were...

background and objectives: methicillin resistant staphylococcus aureus (mrsa) is a major nosocomial pathogen causing significant morbidity and mortality. the aim of this study was to evaluate in vitro activities of different antibiotics against methicillin resistant staphylococcus aureus. materials and method: the study was conducted over a period of one year (january 2009 - december 2009) in t...

During the last two decades, various medicinal plants have been studied for their possible antimicrobial activity to discover new antimicrobial agents capable of resolving problems such as the development of drug resistance in pathogenic microorganisms as well as the side effects of some present antibiotics. In this study, the antibacterial activity of methanolic extract of T. pubescens (rich i...