Thymoglobulin (Thymoglobulin®; Genzyme, Cambridge, Mass., USA) is a polyclonal antibody which has been used in the field of transplantation over the last four decades. With an initial hesitancy, it is widely used now in the prevention and treatment of rejection following renal transplantation. Thymoglobulin's lack of nephrotoxic properties (unlike calcineurin inhibitors) may potentiate it to be...

kaposi᾽s sarcoma (ks) can develop in 0.06% to 4.1% of kidney transplant recipients. here we describe a case of 50-year-old man who developed ks a few months after kidney transplantation . after transplantation, he had delayed graft function and was managed by anti-thymocyte globulin (atg) for five days. at the discharge, his immunosuppressive therapy was prednisolone 20 mg/day, ttacrolimus (ppr...

Venous thromboembolism (VTE) is a life-threatening complication, especially in case of recurrence. The appropriate duration anticoagulant treatment following the first event crucial. Risk factors that increase risk recurrence VTE are many, and include medications, kidney disease, renal transplantation (RT), diagnosis sickle cell disease (SCD). There currently no guidelines define therapy after ...

Data from seven randomized, prospective trials were pooled to determine the effect of steroid-free immunosuppression on allograft survival, patient survival, and the incidence of acute allograft rejection in renal transplant recipients receiving cyclosporine-based maintenance immunosuppression. Six of the seven trials incorporated into this analysis examined the effects of either complete avoid...

Background: Monitoring of phenotypic characteristics of T-lymphocytes in peripheral blood is commonly performed to give the clinical parameters in the management of kidney transplant recipients.   Objective: To predict rejection in renal transplantation by immune parameters. Methods: 16 non-diabetic kidney transplant candidates (4 females and 12 males, age = 20-65 yr, first time transplant) wer...

Renal mucormycosis is a rare and potentially lethal complication of kidney transplantation. We describe two cases of renal mucormycosis following deceased donor kidney transplantation. This is the second report of renal mucormycosis following kidney transplantation in the United States, and the first case of renal mucormycosis infection presumed to be of recipient origin. Case A had an early pr...

Nowadays there is an emerging problem with renal replacement therapy in the world. Its main methods include dialysis and transplantation. However, many regions world do not have access to one or more due numerous economic, social, other factors. Hemodialysis peritoneal are shown be equally efficient, however, it may difficult choose one. For each patient who faced choice of a method therapy, qu...

Cytomegalovirus (CMV) infection and disease, with its extensive direct and indirect consequences, adds considerably to the cost of patient management in both solid organ and bone marrow transplantation. Antiviral prophylaxis for CMV infection can offer cost advantages over preemptive therapy and "wait-and-treat" approaches. Valacyclovir has demonstrated efficacy for CMV prophylaxis in renal, he...

End-stage renal disease (ESRD) is a severe health problem with high mortality and morbidity rates and growing incidence worldwide. Recently, two main renal replacement therapy modalities have been used for ESRD patients: Dialysis and kidney transplantation. It is undoubtedly clear that transplantation is the best choise for long term survival and every transplantation candidate is also a preemp...