This article adopts a holistic view of Alzheimer's disease. Biomedical, psychological and social aspects of the condition are discussed, and aetiology, epidemiology, diagnosis and treatment explored. A range of approaches to working with people with Alzheimer's disease, based on a psychological model of dementia, is described including reminiscence and cognitive stimulation therapy.

Following a non-technical personal reminiscence of the author's conception of Chua's circuit, this paper presents the systematic sequence of technical steps which the author used to design his chaotic circuit. The design procedure. though straightforward in nature. could not have been concocted without a working knowledge of several crucial properties of nonlinear circuits and their physical re...

Reminiscence—the act of recalling or telling others about relevant personal past experiences—plays an important role in the well-being older adults. Therefore, it is to develop intelligent systems aiming at improving elderly by reliably detecting reminiscence their everyday life conversations. Data imbalance one main challenges automatic detection from conversations, as reminiscing a rare event...

BACKGROUND Happiness has a considerable impact on elderly quality of life. Reminiscence therapy can be an effective intervention in increasing the positive emotions among elderly. OBJECTIVES This study was performed to investigate the effect of reminiscence therapy on Iranian elderly women's happiness. PATIENTS AND METHODS This randomized clinical trial conducted on 32 elderly women (census...

The use of clonal analysis to obtain a fate map of the epiblast of the mouse embryo and to investigate cell distribution during gastrulation and early neurulation is described in a personal reminiscence. A revised fate map of the epiblast at 6.5 days gestation is provided, and the development of 3-dimensional, quantitative image analysis techniques outlined.