Journal:
:مجله علوم اعصاب شفای خاتم
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safieh ebrahimi department of medical biochemistry, school of medicine, mashhad university of medical sciences, mashhad, iran
mohammad jalili-nik department of medical biochemistry, school of medicine, mashhad university of medical sciences, mashhad, iran
hossein abde-ahad department of medical biochemistry, school of medicine, mashhad university of medical sciences, mashhad, iran
mahdi hassanian department of medical biochemistry, school of medicine, mashhad university of medical sciences, mashhad, iran
thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...