BACKGROUND Prucalopride is a 5-HT4 receptor agonist with gastrointestinal prokinetic activities. This integrated analysis of data from three 12-week, double-blind trials evaluated the effect of prucalopride 2 mg q.d. on common constipation symptoms in women in whom laxatives had failed to provide adequate relief. The effect of prucalopride on bowel function was outside the scope of the analysis...

The effect of propranolol on ST depression in the praecordial 16 lead electrocardiogram was observed in 52 patients before and after treatment, both at rest and after exercise. In a further 20 patients exercise tests repeated on separate days two months apart showed that the technique gave reproducible results. A variable relation between symptomatic relief and praecordial exercise-induced ST s...

To review the literature on the efficacy of cyclosporine (CsA) ophthalmic emulsion 0.05% on symptomatic relief in chronic dry eye disease. There is consistent evidence of objective improvements in chronic dry eye disease (Schirmer score, corneal and interpalpebral dye staining, and tear breakup time) with CsA, but variable results with symptomatic improvement, possibly due to patient tolerance ...

microstructural evolutions of twinning induced plasticity (twip) steel during tensile straining wereinvestigated by in situ sem observations. the results indicated that slip lines and mechanical twins aswell as surface relief were increased with increasing strain, resulting in a stepped surface. additionally,these deformation mechanisms could change the shape of each grain via shear and rotatio...

The Great Depression offers a unique laboratory to investigate the causal impact of migration on local labor markets. We use variation in the generosity of New Deal programs and extreme weather events to instrument for migrant flows to and from U.S. cities. Inmigration had little effect on the hourly earnings of existing residents. Instead, in-migration prompted some residents to move away and ...

The coordination problem of relief items’ distribution operations is essential in humanitarian relief chains. If the coordination is proper, it will improve the response phase to the crisis. In order to improve the coordination in humanitarian relief chains, distribution and warehousing operations of relief items were outsourced to the third-party logistics. In this paper, the procurement-distr...

Physical and mechanical regularities in the effect of certain processing operations on the shape and roughness of the hydraulic cylinder surface are found. The mechanisms of the spatial self-organization of the relief and surface of bearings under conditions of false brinelling are summarized and analyzed. The data obtained can be used for further scientific generalization or prediction and dia...

b a c k g r o u n d & aim: following the bam earthquake, relief teams and individual volunteers’influx in the scene. we conducted this survey to determine the needs and health status of relief workers when they were in the scene. methods  & materials:   this  was a concurrent  nested  mixed-method  survey  that  the qualitative nested   in  a  quantitative   approach.   interviews   were   thro...