BACKGROUND AND AIMS The burden of premature mortality due to opioid-related death has not been fully characterized. We calculated temporal trends in the proportion of deaths attributable to opioids and estimated years of potential life lost (YLL) due to opioid-related mortality in Ontario, Canada. DESIGN Cross-sectional study. SETTING Ontario, Canada. PARTICIPANTS Individuals who died of ...

To investigate the association between level of alcohol consumption and mortality and hospital admissions, data from the Swedish twin registry were utilized. Twins born in 1925 or later responded to a questionnaire on lifestyle and personality in 1973. A total of 9057 twins were followed in the national cause of death register and in hospital discharge registers through 1992. The proportion of ...

Reports of trends in mortality from neurodegenerative disease have long relied on death certificates registries and other nationally-administered databanks to determine the state and direction of public health regarding these conditions. In this article, Mylne et. al. turned to the Office of National Statistics, England to ascertain the death statistics for patients with Parkinson's disease (PD...

INTRODUCTION Sex-related physiological differences result in different expressions of diseases for men and women. Data are contradicting regarding the increase in the female risk for cardiovascular disease (CVD) at mid-life. Thus, we studied possible sex differences in age-adjusted mortality for CVD and non-vascular diseases stratifying our findings by specific age groups. METHODS Over one mi...

BACKGROUND A reduction in the availability of cholesterol may limit the cellular proliferation required for cancer growth and metastasis. We tested the hypothesis that statin use begun before a cancer diagnosis is associated with reduced cancer-related mortality. METHODS We assessed mortality among patients from the entire Danish population who had received a diagnosis of cancer between 1995 ...

The force of natural selection to eliminate deleterious genes is attenuated with advancing age, allowing senescence to evolve. This suggests that a distinctly marked end of the reproduction period is likely to be followed by an acceleration of senescence. It is thus expected that menopause should trigger an acceleration of age-related mortality increase in human females. Such an abrupt initiati...

In this issue of the Journal of the Chinese Medical Association, we have included an article from the Shihpai Eye Study. Therein, Kuang et al reported the relationship between visual impairment and 3-year mortality among older people in the Shihpai area in the city of Taipei. The association between visual impairment and mortality has been extensively studied over a lengthy period of time. The ...

A saúde infantil, que tem como principal indicador o coeficiente de mortalidade infantil, constitui-se ainda em um importante problema de saúde pública em escala mundial. Uma das Metas de Desenvolvimento do Milênio (Millenium Development Goals – MDG), estabelecidas pelos países e organizações internacionais, é a redução da mortalidade em menores de cinco anos em dois terços no período de 1990 a...

OBJECTIVE Paediatric HIV is a leading cause of morbidity and mortality worldwide. We describe HIV-related mortality in a cohort of HIV-infected Jamaican children and identified factors which influenced survival. METHODS A retrospective descriptive study was conducted for the period March 2003 - December 2005 at Cornwall Regional Hospital, Montego Bay, Jamaica. We summarized demographic and cl...