نتایج جستجو برای: related acute lung injury
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2004;126;249-258 Chest Mark R. Looney, Michael A. Gropper and Michael A. Matthay Review : A * Transfusion-Related Acute Lung Injury http://chestjournal.chestpubs.org/content/126/1/249.full.html services can be found online on the World Wide Web at: The online version of this article, along with updated information and ISSN:0012-3692 ) http://chestjournal.chestpubs.org/site/misc/reprints.xhtml (...
Transfusion of blood products can lead to various transfusion reactions. Transfusion reactions that can cause pulmonary complications are: circulatory overload, anaphylactic reactions, bacterial contamination and transfusion-related acute lung injury (TRALI). TRALI is a rare but life-threatening complication of transfusion. TRALI is now the leading cause of transfusion-related fatalities report...
OBJECTIVE The purpose of this article is to describe the clinical symptoms and illustrate the radiological manifestations of transfusion-related acute lung injury (TRALI) as the condition develops. We mention those findings that aid the discrimination from transfusion-associated cardiac overload. We will also point some of the characteristics that increase the risk of TRALI. CONCLUSION TRALI ...
H. W. Reesink, J. Lee, A. Keller, P. Dennington, J. Pink, R. Holdsworth, H. Schennach, M. Goldman, T. Petraszko, J. Sun, Y. Meng, K. Qian, V. Rehacek, P. Turek, T. Krusius, E. Juvonen, P. Tiberghien, D. Legrand, G. Semana, J. Y. Muller, J. Bux, A. Reil, C. K. Lin, H. Daly, E. McSweeney, L. Porretti, N. Greppi, P. Rebulla, H. Okazaki, S. A. Sánchez-Guerrero, H. A. Baptista-González, C. Martínez-...
(Accepted for publication March 16, 2015.) Center for Biologics Evaluation and Research, the putative cause of TRALI is anti–human leukocyte antigen or granulocyte antibodies in the donor blood product with 89% of TRALI cases having these antibodies.5 Clifford et al. did not present data on these antibodies, but the 2013 SHOT annual report suggested that antibodies were present in 40% of TRALI ...
Transfusion-related acute lung injury (TRALI) is the most common cause of serious morbidity and mortality due to hemotherapy. Although the pathogenesis has been related to the infusion of donor antibodies into the recipient, antibody negative TRALI has been reported. Changes in transfusion practices, especially the use of male-only plasma, have decreased the number of antibody-mediated cases an...
Transfusion-related acute lung injury (TRALI) is a serious and potentially fatal complication of transfusion of blood and blood components. TRALI is under-diagnosed and under-reported because of a lack of awareness. A number of models have been proposed to explain the pathogenesis of TRALI: an antibody mediated model; a two-event biologically active mediator model; and a combined model. TRALI c...
The leading cause of transfusion-related morbidity and mortality in the United States is transfusion-related acute lung injury (TRALI). Diagnostic criteria for TRALI have recently been developed and primarily consist of hypoxia and bilateral pulmonary edema occurring during or within 6 h of a transfusion in the absence of cardiac failure or intravascular volume overload. The primary differentia...
Fatal transfusion related acute lung injury following coronary artery by-pass surgery: a case report
BACKGROUND Transfusion related acute lung injury (TRALI) is a potentially fatal Acute Lung Injury following transfusion of blood components. Hypotheses implicate donor-derived anti-human leukocyte antigen or granulocyte antibodies reacting with recipients' leukocytes, releasing inflammatory mediators. Lack of agreement on underlying cellular and molecular mechanisms renders improving transfusio...
PURPOSE OF REVIEW Patients who experience severe trauma are at increased risk for the development of acute lung injury and acute respiratory distress syndrome. The management strategies used to treat respiratory failure in this patient population should be comprehensive. Current trends in the management of acute lung injury and acute respiratory distress syndrome consist of maintaining acceptab...
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