نتایج جستجو برای: regulated and 69 down

تعداد نتایج: 16868431  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی اصفهان 1389

run-out-table (rot) is located between last finishing stand and down coiler in a hot strip mill. as the hot steel strip passes from rot, water jets impact on it from top and bottom and strip temperature decreases approximately from 800-950 °c to 500-750°c. the temperature history that strip experience while passing through rot affects significantly the metallurgical and mechanical properties, s...

Journal: :gastroenterology and hepatology from bed to bench 0
sayyad khanizadeh mehrdad ravanshad seyed younes hosseini parivash davoodian azim nejati zadeh jamal sarvari

aim : in this study, to clarify the smad4blocking impact on fibrosis process, we investigated its down-regulation by shrna on activated human lx-2 cell, in vitro.   background : liver fibrosis is a critical consequence of chronic damage to the liver that can progress toward advanced diseases, liver cirrhosis and hepatocellular carcinoma (hcc).  different smad proteins play as major mediators in...

2008
J. Gong N. Li W. Zhu X. Gao J. Li M. Papp I. Altorjay N. Dotan K. Palatka I. Foldi J. Tumpek S. Sipka M. Udvardy L. Lakatos A. Kovacs Z. Tulassay P. Miheller T. Szamosi B. Wiedenmann A. Dignass E. F. Stange

s of the 3rd ECCO Congress, Lyon, France, February 28–March 1, 2008 79 Results: A significant differential expression of genes is found comparing Treg from HC to aCD (69 genes, 39 up-, 30 down-regulated) and HC to iCD (52 genes, 25 up-, 27 down-regulated). In both groups, 10 genes were upregulated more than 5fold. Transcripts for CCR4 were among the strongest expressed and showed an up-regulati...

2016
Xi Jin Chun-yan Feng Zun Xiang Yi-peng Chen You-ming Li

The pathogenesis of nonalcoholic steatohepatitis (NASH) is still unclear, where involvement of circRNA is considered for its active role as "miRNA sponge". Therefore, we aimed to investigate the circRNA expression pattern in NASH and further construct the circRNA-miRNA-mRNA network for in-depth mechanism exploration. Briefly, NASH mice model was established by Methionine and choline deficiency ...

Patients with impaired immunity are at particular risk of infections with Candida albicans. Antifungal drugs such as azoles commonly used for candidiasis treatment, but drug resistance is one of the most common problems for public health. The aim of this study was to evaluate the expression of lanosterol 14-demethylase (ERG11) gene for three-drug combinations in C. albicans. Disk diffusion and ...

Objective(s): Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of multiple sclerosis. The aim of the present work is to investigate the protective effects of erythropoietin against cuprizone-induced oxidative stress. Materials and Methods: Adult male C57BL/6J mice were fed a chow containing 0.2 % cuprizone for 6 ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده ادبیات و علوم انسانی 1392

in new management approaches, in the organizations with inflexible structure, existing of red tapes and interruptions caused by limitations and also non-compliance with environmental changes, create demotivation among staff. with regard to the influence of job motivational potential and its relationship to the type of organizational structure( enabling and dissuasive), the goal of this research...

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