نتایج جستجو برای: reduced chemistry

تعداد نتایج: 689773  

2014
Eamon Comer Jennifer A. Beaudoin Nobutaka Kato Mark E. Fitzgerald Richard W. Heidebrecht Maurice duPont Lee Daniela Masi Marion Mercier Carol Mulrooney Giovanni Muncipinto Ann Rowley Keila Crespo-Llado Adelfa E. Serrano Amanda K. Lukens Roger C. Wiegand Dyann F. Wirth Michelle A. Palmer Michael A. Foley Benito Munoz Christina A. Scherer Jeremy R. Duvall Stuart L. Schreiber

Here, we describe medicinal chemistry that was accelerated by a diversity-oriented synthesis (DOS) pathway, and in vivo studies of our previously reported macrocyclic antimalarial agent that derived from the synthetic pathway. Structure-activity relationships that focused on both appendage and skeletal features yielded a nanomolar inhibitor of P. falciparum asexual blood-stage growth with impro...

2009
H Rajak

In the present scenario, pharmaceutical companies are under pressure to speed-up their drug discovery programmes and to lower the cost of discovering new medicines. Combinatorial chemistry and high through put synthesis are almost well established as potential means of speeding up the drug discovery process, these techniques have been embraced widely by the pharmaceutical industry but there is ...

2002
D. Wiebe D. Semenov Th. Henning

We present a new method to analyse and reduce chemical networks and apply this technique to the chemistry in molecular clouds. Using the technique, we investigated the possibility of reducing the number of chemical reactions and species in the UMIST 95 database simultaneously. In addition, we did the same reduction but with the " objective technique " in order to compare both methods. We found ...

2010
Patrick Huber Bruno Carré

Biocide programs have become necessary in most fine paper manufacturing circuits, as drastic reduction of fresh water consumption in the industry enhances microbial development. Depending on their chemical nature, biocides may interfere with typical wet-end chemistry additives and furnish. A reference wet-end chemistry was set (including fixing aid, dry strength aid, sizing agent, and retention...

2012
Rina Das Dinesh Mehta Harsh Bhardawaj

Microwave-assisted organic synthesis is an enabling technology for accelerating drug discovery and development processes. Microwave organic synthesis opens up new opportunities to the synthetic chemist in the form of new reaction that are not possible by conventional heating and serve a flexible platform for chemical reaction. This review focuses on the advances in the developing of innovative ...

2010
Timothy D. Meehan Michael S. Crossley Richard L. Lindroth

Human alteration of atmospheric composition affects foliar chemistry and has possible implications for the structure and functioning of detrital communities. In this study, we explored the impacts of elevated carbon dioxide and ozone on aspen (Populus tremuloides) leaf litter chemistry, earthworm (Lumbricus terrestris) individual consumption and growth, and springtail (Sinella curviseta) popula...

کلاگری, علی اصغر, عابدینی, علی , کنگرانی فراهانی, فاطمه ,

Zan lateritic horizon is located about 25 km southeast of Damavand, Tehran Province. This horizon developed as stratiform in lower part of shales and sandstones of Shemshak Formation (Jurassic). Mineralogical investigations show that diaspore, hematite, goethite, anatase, and kaolinite are the principal minerals of this horizon accompanied by lesser amounts of accessory minerals like boehmite, ...

Journal: :iranian journal of catalysis 2014
mohadeseh seddighi

mohaddeseh seddighi was born in rasht, guilan, i. r. iran (1985). she received b.sc. in applied chemistry from isfahan university of technology (iut) (2007) and his m.sc. in organic chemistry from isfahan university of technology (2010) under the direction of professor abdol. r. hajipour. she began her ph.d. studies at university of guilan under supervision of professor farhad shirini from 2011...

Journal: :The Astrophysical Journal 2021

We have investigated the chemistry of dense interstellar clouds and found new bistable solutions in nitrogen carbon chemistries. identify autocatalytic processes that are present pure, reduced, chemical networks and, as previously for oxygen chemistry, He$^+$ plays an important role. The applicability these results to astronomical environments is briefly discussed. occur low densities high ioni...

Journal: :iranian journal of catalysis 2013
maryam mashhadinezhad

maryam mashhadinezhad was born in rasht, guilan, i. r. iran. she received her b. sc in chemistry in 2009 from the university of guilan and her m.sc. in organic chemistry in 2011 from the same university. she is studying under the supervision of dr. farhad shirini for her ph. d. her research interests include the use of heterogeneous catalysts in organic reactions.

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