The current supply of red blood cells expressing rare blood groups is not sufficient to cover all the existing transfusion needs for chronically transfused patients, such as sickle cell disease homozygous carriers, because of alloimmunization. In vitro production of cultured red blood cells is slowly emerging as a possible complement to the existing collection-based red blood cell procurement s...

Maassen, N., M. Foerster, and H. Mairbäurl. Red blood cells do not contribute to removal of K1 released from exhaustively working forearm muscle. J. Appl. Physiol. 85(1): 326–332, 1998.—K1 released from exercising muscle via K1 channels needs to be removed from the interstitium into the blood to maintain high muscle cell membrane potential and allow normal muscle contractility. Uptake by red bl...

Transfusion affects the immune response to renal transplantation and may be associated with recurrence of various human neoplasms. Data from patients with colonic, rectal, cervical, and prostate tumours showed an association between transfusion of any amount of whole blood or larger amounts of red blood cells at the time of surgery and later recurrence of cancer. Recipients of one unit of whole...

Photoresponsive block copolymers (PRBCs) containing azobenzenes and other chromophores can be easily prepared by controlled polymerization. Their photoresponsive behaviors are generally based on photoisomerization, photocrosslinking, photoalignment and photoinduced cooperative motions. When the photoactive block forms mesogenic phases upon microphase separation of PRBCs, supramolecular cooperat...

Blood transfusion is a well-accepted medical technology that currently relies on a supply of red blood cells from many thousands of altruistic donors. Cultured red blood cells using stem cell technology could offer a replacement technology, providing a limitless supply of red blood cells from a single source. This project used interviews and focus groups to explore the views of a wide range of ...

Many diseases such as Cancer, Huntington’s disease, Malaria, Multiple Sclerosis, and Myalgic Encephalomyelitis are mainly diagnosed by the appearances include size, shape, color and the double-concave dish size of red blood cells in the blood smear. The automatically evaluating process in the appearances from the blood smear images is high importance for rapid and accurate diseases diagnosis. T...

background: falciparum malaria is a severe health burden worldwide. antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. malarial hemozoin (hz), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. objective: to determine the immunological impact of hemozoin on the capacity ...