although abo incompatibility between mother and fetus has long been suspected as cause of spontaneous abortion in man, its precise contribution has not been completely resolved. in spite of reports in which the incompatible mating was recognized to be a cause of habitual abortion, and which eventually results in infertility or a reduction in the number of living children compared with the numbe...

Chromosomal abnormality is the most common genetic cause of male infertility, particularly in cases of azoospermia, oligozoospermia, and recurrent spontaneous abortion. Chromosomal rearrangement may interrupt an important gene or exert position effects. The functionality of genes at specific breakpoints, perhaps with a specific role in spermatogenesis, may be altered by such rearrangements. Str...

objective herpes simplex virus (hsv) infection during pregnancy may lead to fetal loss. the aim of this study was to explore the infection rate of hsv type 1 and 2 infection associated with spontaneous abortion in a pilot case-control study in two cities of iran in 2010. patients and methods placenta and curettage samples from 35 healthy full term neonates and 35 cases of spontaneous abortion w...

introduction: a factor known to cause thrombophilia in women with recurrent pregnancy loss (rpl) is the a1298c polymorphism of methylenetetrahydrofolate reductase gene (mthfr). this study aimed to determine the association between rpl and this polymorphism in iranian patients. methods: in this case-control study, 30 patients with a previous history of two or more consecutive unexplained abortio...

background & aim: occupational exposures can cause problems such as reproductive system disorders; however, the effects of some exposures, such as psychological stress, have not been investigated yet. this study aims to investigate the effects of women’s psychological stress on obstetric disorders. methods:this historical cohort study was conducted on 1400 working women in mashhad, iran. data c...

ureaplasma urealyticum can colonize women genital tract and be isolated from the amniotic fluid of women with adverse pregnancy outcomes. the association of u. urealyticum with spontaneous abortion remains controversial. the aim of this study was to evaluate the frequency of u. urealyticum infection among pregnant women and its association with spontaneous abortion.in this case-control study we...

In mammalian females, diploid somatic cells contain two X chromosomes, one of which is transcriptionally silenced, in a process termed X chromosome inactivation (XCI). Whereas XCI is largely random in placental females, many women exhibit skewed XCI (SXCI), in which the vast majority cells have the same X chromosome inactivated. SXCI has serious health consequences, associated with conditions r...