OBJECTIVE To determine whether multidisciplinary disease management programmes for patients with coronary heart disease improve processes of care and reduce morbidity and mortality. DATA SOURCES Randomised clinical trials of disease management programmes in patients with coronary heart disease were identified by searching Medline 1966-2000, Embase 1980-99, CINAHL 1982-99, SIGLE 1980-99, the C...

The acute occlusion of a coronary artery without the evidence of myocardial infarction might immediately affect both the diagnosis and treatment of coronary artery disease. We present the case with a sudden occlusion of the left main coronary artery without typical chest pain following an exercise tolerance test and rapid spontaneous reperfusion of the left main coronary artery.

The effect of untreated total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) as cardiovascular risk factors in both primary and secondary prevention has been extensively investigated. The predictive value of on-treatment lipid and apolipoprotein levels on subsequent cardiovascular events is as yet uncertain. Eight hundred forty-eight patients (675 men and 173 women) with angio...

Acute myocardial infarction (MI) patients remain at high risk for recurrent events. Cholesterol efflux, mediated by apolipoprotein A-I, removes excess cholesterol from atherosclerotic plaque and transports it to the liver excretion. Impaired efflux is associated with higher cardiovascular (CV) event rates among both stable coronary artery disease recent MI. CSL112, a novel intravenous formulati...

Verma and colleagues reported an interesting case of recurrent fever of immunological origin [1]. The first episode probably favors a diagnosis of Kawasaki disease because of the presence of coronary artery dilatation, which normalized with anti-inflammatory therapy. During the second episode, the child had high-grade fever with oral mucosal changes and cervical lymphadenopathy with no identifi...

discussion the reason is that we assess the relative and not absolute differences of the tracer uptake in this imaging modality. there may be other findings on mpi images which could help us overcome this pitfall, including detecting wall motion abnormalities, lung uptake of the tracer, or transient ischemic dilation. another important issue is the ecg changes during exercise stress testing, wh...

although coronary artery disease (cad) is not common among individuals younger than 40-45 years of age, a small percentage of this age group needs to undergo surgical revascularization because of cad. why some people are at higher risk of developing premature cad is not clearly known. increased number of traditional risk factors or genetic predisposition may play significant roles in this regar...