To complete the review article by Abes and colleagues (Pharmaceuticals 2010, 3, 146-157) which provides a good overview on recently developed approaches for generation of glyco-modified antibodies and the impact of glyco-modification of antibodies on their effector functions, important information should be added, namely that - besides the Glycart and the Biowa approach to generate de-fucosylat...

Why are you trying to anticipate contamination that does not yet exist? The standard paradigm of environmental chemistry is that we chase the effect of a chemical in the environment, so there’s a lag between discovering a problem and then 10 years later developing a solution. In the 1970s and 1980s, the targets were pesticides, then chlorinated solvents in the 1990s. And in the 2000s, people fo...

The Pharmaceutical Benefits Advisory Committee (PBAC) plays an important role in controlling the drugs that are available at subsidised prices under the Pharmaceutical Benefits Scheme (PBS). In brief, the Committee provides advice on whether a new drug is sufficiently cost-effective to merit its being added to the PBS. Listing is important to the drug manufacturers, because it has a beneficial ...

Spencer Phillips Hey and Aaron Kesselheim propose that informativeness-asserting scientific facts-rather than truthfulness ought to be the standard for regulating commercial speech about pharmaceuticals.