The goal of this research is to develop a spectrofluorometric method for analyzing carvedilol in pharmaceutical preparations and apply the formulations. method’s calibration curve was plotted between 25 500 ng/mL. mean equation from six replicate experiments y=1.8736x+7.7291. correlation coefficient value higher than 0.997 curve. trueness results were better 2.09% precision less 2.73% carvedilo...

OBJECTIVE To explore the course and timing of functional recovery in patients who have emerged from coma after undergoing severe traumatic brain injury. METHODS An observational study involving 19 patients with traumatic brain injury recovered from coma who underwent holistic, intensive and multidisciplinary neurorehabilitation. Daily performance in each cognitive function (long-term memory, ...

Diffusion processes in the lumen of the endoplasmic reticulum of tissue derived cells are investigated using a computational approach based on the method of particle strength exchange. 3D reconstructions of the shape of the endoplasmic reticulum are made from micrograph sections and are then used to conduct direct numerical simulations of fluorescence recovery experiments. The influences of the...

It has been demonstrated that short-term habituation may be caused by a decrease in release of presynaptic neurotransmitters and long-term habituation seems to be caused by morphological changes of presynaptic terminals. A parsimonious model of short-term and long-term synaptic plasticity at the electrophysiological level is presented. This model consists of two interacting differential equatio...

A voltage-clamp analysis of the effect of almokalant on the delayed rectifier K' current (IK) was made in rabbit ventricular myocytes. The two-suction pipette method was used, and appropriate voltage-clamp protocols were used to study more specifically use dependence, block development, and recovery from block. Almokalant interacted with the IK in two ways: it shifted the activation curve in th...

Low levels of educational attainment and low socioeconomic status have been significantly linked to poor health and increased incidence of disease, including Alzheimer's disease and diseases of the cardiovascular, pulmonary, renal, and gastrointestinal systems. Our goal in the present study was to determine the degree to which educational level and socioeconomic status influence initial severit...

Chromium is one of the hazardous pollutants in industrial effluents. In this study, a new nano-boehmite modified with sodium dodecyl sulphate is developed for preconcentration trace amounts of chromium ions as a prior step to its determination by flame atomic absorption spectrometry. We investigated the effect of various parameters on the recovery of the analyte ions, including pH of sample solut...

Effects of two general anesthetics, halothane and thiamylal, on the fast sodium inward current (INa) of enzymatically isolated single rat ventricular cells were studied under current clamp and voltage clamp conditions. A suction pipette technique was used for potential measurement, current injection and internal perfusion of isolated cells. In current clamp experiments, sodium action potential ...