نتایج جستجو برای: receptors

تعداد نتایج: 224569  

Journal: :مجله دانشگاه علوم پزشکی شهید صدوقی یزد 0
سعیده کریمی s karimi مهناز طاهریانفرد m taherianfard امین ا... بهاءالدینی a bahaoddini مهدی فاضلی m fazeli

introduction: the aim of the present study is to investigate the effect of interaperitoneal injection of baclofen (gaba-b agonist) and cgp35348 (gaba-b antagonist) on serum testosterone concentration in aggressive rats exposed to electromagnetic field. methods: fifty five mature male rats weighing 200±20 grams were studied. animals were divided into 2 main groups and four subgroups. main groups...

Journal: :caspian journal of internal medicine 0
keykhosro mardanpour mahtab rahbar

background: fine-needle aspiration of breast cancer often provides moderate cellular material that is representative of the tumors. these samples can be used not only for cytological diagnosis but also to obtain information on the prognosis and likely response to therapy by using immunohistochemical staining studies. methods: we assessed the degree of correlation between prognostic biologic mar...

Journal: :iranian journal of immunology 0
mir davood omrani department of genetics mohammad reza mokhtari department of urology and nephrology, uromia university of medical science, uromia, iran ali tagizadae department of urology and nephrology, uromia university of medical science, uromia, iran morteza bagheri department of genetics pedram ahmad-poor department of urology and nephrology, uromia university of medical science, uromia, iran

background: despite advances in the medical care of renal transplant recipients which have led to an improvement in allograft survival, renal allograft rejection is still a major ob-stacle to successful organ transplantation. understanding the mechanisms contributing to allograft rejection will be of great importance for the development of efficient antirejection strategies. objective: the aim ...

Journal: :iranian journal of basic medical sciences 0
nasim dana applied physiology research center, cardiovascular research institute, isfahan university of medical sciences, isfahan, iran shaghayegh haghjooy javanmard applied physiology research center, cardiovascular research institute, isfahan university of medical sciences, isfahan, iran laleh rafiee applied physiology research center, cardiovascular research institute, isfahan university of medical sciences, isfahan, iran

objective(s): herbal medicines are promising cancer preventive candidates. it has been shown that punica granatum l. could inhibit angiogenesis and tumor invasion. in this study, we investigated whether the anti-angiogenic effect of pomegranate peel extract (ppe) is partly attributable to peroxisome proliferator-activated receptors (ppars) activation in the human umbilical vein endothelial cell...

Journal: :journal of agricultural science and technology 2013
a. gholibeikifard m. aminafshar m. hosseinpour mashhadi

baluchi sheep is considered as the most common breed in iran, constituting about 30% of total sheep population, approximately 15 million heads. this research was designed to study the incidence of mutation in two loci of igf-i (exon 3) and adrb3 (intron) along with their association with body weight traits in baluchi sheep population. following dna extraction from 190 baluchi sheep, two pairs o...

Journal: :iranian journal of pathology 2015
sepideh siadati majid sharbatdaran novin nikbakhsh naser ghaemian

background and objectives: breast cancer is the most common malignancy among women in the world. the aim of this study was to assess estrogen receptor (er), progesterone receptor (pr) and her-2/neu of infiltrating ductal carcinoma (idc) with tumor size, histologic grade, lymph node metastasis and age. methods: this study was carried out on 300 tissue blocks ofpatients with idc who underwent mas...

Journal: :research in molecular medicine 0
aleksandr zherebiatiev senior technician of department of microbiology, virology, and immunology, zaporozhye state medical university, mayakovsky avenue 26, zaporozhye, 69035, ukraine aleksandr kamyshnyi 1department of microbiology, virology, and immunology, zaporozhye state medical university, zaporozhye, ukraine

background: the pathogenesis of inflammatory bowel disease is complex and multifactorial. studies have led to the current concept that toll-like receptors represent key mediators of innate host defense in the intestine, and they are involved in maintaining mucosal as well as commensal homeostasis. we studied the possibility of simvastatin and antagonist of receptors of interleukin-1 for pharmac...

Journal: :Research results in pharmacology 2022

Introduction : The present study is aimed at investigation of the mechanism action a new 3-substituted thietane-1,1-dioxide derivative (N-199/1) exhibiting antidepressant properties, in several tests neuropharmacological interaction. Materials and methods To N-199/1, its effect on 5-hydroxytryptophan (5-HTP)-induced head-twitch response (50 mg/kg 300 mg/kg), haloperidol-induced catalepsy (1 are...

Journal: :IUPHAR/BPS guide to pharmacology CITE 2023

Pattern Recognition Receptors (PRRs, [110]) (nomenclature as agreed by NC-IUPHAR sub-committee on Receptors, [20]) participate in the innate immune response to microbial agents, stimulation of which leads activation intracellular enzymes and regulation gene transcription. PRRs express multiple leucine-rich regions bind a range microbially-derived ligands, termed PAMPs or pathogen-associated mol...

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