In this chapter, we will introduce the basic concepts that constitute what is known as ReliabilityCentered Maintenance. Initially, however, we will briefly discuss how PM has evolved in the industrial world, and most importantly, we will look at how one of the basic tenets of reliability engineering—the “bathtub curve”—can and should influence the formulation of PM tasks. Next, we will look at ...

This ESG Lab Review documents the benefits of leveraging VCE Vision Intelligent Operations with VCE converged infrastructure systems and the VCE Release Certification Matrix (RCM) to simplify the process of upgrading a complete IT infrastructure. Both quantitative and qualitative evaluations of the time to upgrade four common infrastructure deployments were conducted: a traditional “do it yours...

In vivo reflectance confocal microscopy (RCM) is a modern, non-invasive imaging technique, which allows for real-time examination of the upper layers of the skin at a resolution similar to that of classic microscopy. In addition, it has the advantage of real-time evaluation of blood flow and dynamic monitoring of cutaneous changes while preserving tissue integrity. The present study reported on...

Covalent attachment of ubiquitin marks substrates for proteolysis, but features that identify ubiquitination targets such as chicken egg white lysozyme are poorly understood. Recognition of lysozyme first requires reduction of Cys-6 Cys-127, one of its four native disulfide bonds, and Cys-6,Cys-127-carboxymethylated (6,127-rcm) lysozyme can mimic this three-disulfide intermediate. The 6,127-rcm...

Radiographic contrast media: A new risk for pulmonary aspiration ? Joseph Eldor (1), Vladimir Kotlovker (2), Virgil Priscu (3) Department of Anesthesia, Kaplan Medical Center, Hebrew University and Hadassah, Rehovot, Israel (1)(2) Senior staff Anesthesiologist (3) Head of Department Aspiration of high osmolar water soluble radiographic contrast media (RCM) is dangerous and can induce sever...

Mutants of Neurospora crassa unable to participate in vegetative hyphal fusion (anastomosis) were isolated and characterized. From this analysis, three genes, rcm-1, rco-1 and ham-5, were identified and shown to be required for hyphal fusion. The rcm-1 and rco-1 genes are homologues of the Saccharomyces cerevisiae SSN6 and TUP1 genes, which encode a dimeric transcription factor in yeast. We dem...

Reflectance confocal microscopy (RCM) is an effective, non-invasive pre-screening tool for skin cancer diagnosis, but it requires extensive training and experience to assess accurately. There are few quantitative tools available to standardize image acquisition and analysis, and the ones that are available are not interpretable. In this study, we use a recurrent neural network with attention on...

Recessive congenital methemoglobinemia (RCM) is a very rare disorder caused by NADH- cytochrome b5 reductase (cytb5r) deficiency. It has been classified into four types. Type I presents with mild cyanosis due to a significant deficiency of cytb5r in erythrocytes only. In type II, the deficiency occurs in all tissues and causes growth and mental retardation and other neurological impairments. RC...

BACKGROUND The aim of our study was to compare myocardial mechanics of constrictive pericarditis (CP) with restrictive cardiomyopathy (RCM), or healthy controls; to assess the impact of pericardial thickening detected by cardiac magnetic resonance on regional myocardial mechanics in CP; and to quantitate the effect of pericardiectomy on myocardial mechanics in CP. METHODS AND RESULTS Myocardi...

Restrictive cardiomyopathy (RCM) is the least common among cardiomyopathies. It can be idiopathic, familial, or secondary to systematic disorders. Marked increase in left and/or right ventricular filling pressures causes symptoms and signs of congestive heart failure. Electrocardiographic findings are nonspecific and include atrioventricular conduction and QRS complex abnormalities and supraven...