نتایج جستجو برای: rbp4
تعداد نتایج: 415 فیلتر نتایج به سال:
Polycystic ovary syndrome (PCOS) is associated with infertility, increased androgen levels, and insulin resistance. In adipose tissue, zinc facilitates insulin signaling. Circulating zinc levels are altered in obesity, diabetes, and PCOS; and zinc supplementation can ameliorate metabolic disturbances in PCOS. In adipose tissue, expression of zinc influx transporter ZIP14 varies with body mass i...
Retinitis Pigmentosa (RP) is a common form of retinal degeneration characterized by photoreceptor degeneration and retinal pigment epithelium (RPE) atrophy causing loss of visual field and acuities. Exome sequencing identified a novel homozygous splice site variant (c.111+1G>A) in the gene encoding retinol binding protein 4 (RBP4). This change segregated with early onset, progressive, and sever...
One of the most common public liver diseases over world is fatty which contain alcoholic and non-alcoholic liver. One-fourth among general population are impact Non-Alcoholic Fatty Liver Disease (NAFLD) in worldwide.Retinol binding protein 4 (RBP4) known as an adipokine, mainly synthesized secreted from form adipose tissues. RBP4 acts a transporter specifically bound to retinol others Visfatin ...
Plasma transthyretin (TTR) is a plasma protein secreted by the liver that circulates bound to retinol-binding protein 4 (RBP4) and its retinol ligand. TTR is the sole plasma protein that reveals from birth to old age evolutionary patterns that are closely superimposable to those of lean body mass (LBM) and thus works as the best surrogate analyte of LBM. Any alteration in energy-to-protein bala...
Vitamin A must be adequately distributed within the body to maintain the functions of retinoids in the periphery and chromophore production in the eyes. Blood transport of the lipophilic vitamin is mediated by the retinol-binding protein, RBP4. Biochemical evidence suggests that cellular uptake of vitamin A from RBP4 is facilitated by a membrane receptor. This receptor, identified as the Stimul...
BACKGROUND Valproic acid (VPA) is an antiepileptic and anti-migraine prophylactic drug. VPA exhibits two severe side effects, namely acute liver toxicity and teratogenicity. These side effects are usually seen at the genetic and somatic levels. The cited action mechanisms involve inhibition of histone deacetylase, hypofolatenemia, hyperhomocysteinemia, and reactive oxidative stress. The proteom...
This analysis evaluated the association between serum retinol levels and risk of head and neck cancer (HNC) and whether the association is modulated by the use of alcohol, betel quid, or cigarette. In addition, we also examined the association between HNC risk and 2 single nucleotide polymorphisms, TTR rs1667255 and RBP4 rs10882272, that have been associated with serum retinol levels. Unconditi...
هدف: تاثیرات مثبت تمرین تناوبی شدید (HIIT) بر تقویت مسیرهای متابولیسم بافت عضلانی سالم به اثبات رسیده است. از جمله هدفهای دیابت تخریب متابولیسم گلوکز و چربی عضله میباشد، لذا هدف از مطالعه حاضر بررسی اثر 8 هفته تمرین تناوبی شدید بر تعدیل بیان ژنی پروتئین متصل به رتینول 4 (RBP4) و پروتئین کیناز فعال‌شده با AMP (AMPK) در عضله نعلی رتها می باشد. روشها: 60 رت نر ویستار (سن: 8 هفته، وزن20±250گرم...
زمینه و هدف : افزایش سن و تغییرات هورمونی در هنگام یائسگی باعث تغییر عملکرد در برخی سیستم های فیزیولوژیکی بدن می گردد و به طور منحصر به فردی زنان را در معرض بیماری کبد چرب غیر الکلی (NAFLD) قرار می دهد. هدف از این مطالعه بررسی اثر تمرین هوازی- مقاومتی برغلظت سرمی رتینول متصل به پروتئین۴، چاقی شکمی و شاخص های متابولیکی در زنان یائسه مبتلا به کبد چرب غیر الکلی بود. مواد و روش ها: ۲۴ زن یائسه غیر...
Abstract Over weight is one of the most important public health concerns and the most common fat metabolism disorder in humans the purpose of this study was to compare the effect of eight weeks of interval training and vitamin D intake on DPP4 and RBP4 plasma levels of overweight with mean age of 39.92±4.15 , height 159.25±3.8 cm weight 72.73 kg /m2 in this study , 40 subjects were selected pur...
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