background and objectives: study of deleterious effect of neurotoxins on the animals' brain is a fascinating research plan. in this project, the damage effect of colchicine on the hippocampal cornu ammonis 1 (ca1) was examined by the studying the hippocampal tissue. materials and methods: injections of colchicine (1-75 μg/rat, intra- hippocampal ca1) were performed in cannulated male wistar rat...

introduction: the present study used a histological evaluation method to examine the effects of pentoxifylline (ptx) on healing an experimentally-induced pressure sore in a rat model. materials and methods: there were 36 adult male rats used in this study. under general anesthesia and sterile conditions, we used forceps to create one pressure sore on each rat. a double layer of folded skin from...

buckwheat rutin has been found to be able to inhibit angiotensin ii (angii) - induced hypertrophy in cultured neonatal rat cardiomyocytes, but the mechanism remains uncertain. in this study, myocardial hypertrophy model was made by adding angii to the medium of cardiac myocytes of neonatal rats, meanwhile, different concentrations of buckwheat rutin were applied to observe their effects. intrac...

background: the purpose of this study is to evaluate effects of teucrium polium (tp) leaf extracts on adenosine monophosphate activated protein kinase (ampk) level in isolated pancreases. materials and methods: in this experimental study, two groups of rats were used as a control group, and diabetic group. in the end of experimental period the animals were sacrificed then pancreas were removed,...

Background: Disturbance of the gut microbiota may play a critical role in progression nonalcoholic fatty liver disease (NAFLD) induced by high-fat diet (HFD). Changes were analyzed rat HFD-induced NAFLD model following treatment with Qinghua Fang (QHF), Chinese herbal formula currently used clinical practice traditional medicine.