introduction: an otogenic brain abscess is a common ent problem but an otogenic trapezius abscess can also be experienced in otolaryngological practice, particularly in patients with chronic suppurative otitis media.   case report: we report a rare case of a trapezius abscess in an eight-year-old girl who presented at the ent, head and neck surgery postgraduate medical institute, lady reading h...

The role of rare variants has become a focus in the search for association with complex traits. Imputation is a powerful and cost-efficient tool to access variants that have not been directly typed, but there are several challenges when imputing rare variants, most notably reference panel selection. Extensions to rare variant association tests to incorporate genotype uncertainty from imputation...

Although rare variants within the Toll-like receptor signalling pathway genes have been found to underlie human primary immunodeficiencies associated with selective predisposition to invasive pneumococcal disease (IPD), the contribution of variants in these genes to IPD susceptibility at the population level remains unknown. Complete re-sequencing of IRAK4, MYD88 and IKBKG genes was undertaken ...

Aortic dissection occurs when a tear develops in the wall of the aorta, which is rare in the young population. This fatal disorder is hard to diagnose, especially in young patients. We present the case of aortic dissection in a 15-year-old boy referred to the Emergency Department of Yazd University of Medical Sciences in November 2015. The patient presented to our department with sudden acute c...

Background: Breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. In this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein.Case Presentation: A 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mont...

We consider a fitness-structured population model with competition and migration between nearest neighbors. Under a combination of large population and rare migration limits we are particularly interested in the asymptotic behavior of the total population partition on supporting trait sites. For the population without mutation on a finite trait space we obtain the equilibrium configuration and ...

background: breast cancer is the most common type of malignancy in the female population, rarely is reported by thromboembolic events during the course of the disease. in this case, we present a rare case of breast cancer presenting as deep vein thrombosis of the axillary vein.case presentation: a 40-year- old female was admitted due to pain and swelling of her right arm and forearm of two mont...

PURPOSE Epidemiologic information on rare cancers is scarce. The project Surveillance of Rare Cancers in Europe (RARECARE) provides estimates of the incidence, prevalence and survival of rare cancers in Europe based on a new and comprehensive list of these diseases. MATERIALS AND METHODS RARECARE analysed population-based cancer registry (CR) data on European patients diagnosed from 1988 to 2...

malignant germ-cell tumors (mgct) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. endodermal sinus tumor (est) forms the most common histologic subtype of mgct. the vagina is an extremely rare site for gcts. an 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. she was pale and a mass was palpable ...