نتایج جستجو برای: rare bleeding disorders

تعداد نتایج: 934255  

Journal: :Frontiers in human neuroscience 2016
Silvia Riva Serena Oliveri Chiara Fioretti Marianna Masiero Gabriella Pravettoni

Coagulation disorders concern a deficiency of the body’s functional ability to regulate blood clotting (Peyvandi and Mannucci, 1999). Disorders in thisarea, which may be genetic or acquired, will result in hemostasis-related problems, including different clinical syndromes from easy bleeding or bruising (so-called “hemophilia”) to inappropriate thrombosis (so-called “thrombophilia”; Weisberg, 1...

Journal: :journal of dentistry, tehran university of medical sciences 0
andre peisker department of cranio-maxillofacial & plastic surgery, jena university hospital, jena, germany. gregor franziskus raschke department of cranio-maxillofacial & plastic surgery, jena university hospital, jena, germany. arndt guentsch center of dental medicine, jena university hospital, jena, germany ; department of surgical sciences, marquette university, school of dentistry, milwaukee, wisconsin, usa. korosh roshanghias dentist, private practice, berlin, germany. stefan schultze-mosgau professor, department of cranio-maxillofacial & plastic surgery, jenauniversity hospital, jena, germany.

oral surgery in patients with bleeding disorders is associated with a high risk of bleeding during and after surgery. this article is aimed to present the case of an eight-year-old girl suffering from severe fanconi anemia with pancytopenia who underwent a dental extraction. the hemostatic effect of local administration of tranexamic acid in combination with a primary suture seems to be extreme...

Journal: :Blood 2021

Abstract Cyclic thrombocytopenia (CTP) is a rare disease, which characterized by periodic fluctuation of the platelet count. The pathogenesis CTP unknown and most likely heterogeneous. Patients with are almost always misdiagnosed as having primary immune (ITP). interval between ITP diagnosis can be many years. patients often receive ITP-specific therapies including corticosteroids, thrombopoiet...

Mohammad Hammoud, Mohammad Kajiyazdi, Peyman Eshghi,

Congenital factor X deficiency is a rare autosomal recessive bleeding disorder that presents with variable bleeding tendency and prolonged coagulation tests, prothrombin time, and partial thromboplastin time. Thromboembolic events have not been reported in patients with factor X deficiency yet. Herein, we report a patient with factor X deficiency who had recurrent venous thromboembolic events.

2018
José M. Bastida María L. Lozano Rocío Benito Kamila Janusz Verónica Palma-Barqueros Mónica Del Rey Jesús M. Hernández-Sánchez Susana Riesco Nuria Bermejo Hermenegildo González-García Agustín Rodriguez-Alén Carlos Aguilar Teresa Sevivas María F. López-Fernández Anna E. Marneth Bert A. van der Reijden Neil V. Morgan Steve P. Watson Vicente Vicente Jesús M. Hernández-Rivas José Rivera José R. González-Porras

Inherited platelet disorders are a heterogeneous group of rare diseases, caused by inherited defects in platelet production and/or function. Their genetic diagnosis would benefit clinical care, prognosis and preventative treatments. Until recently, this diagnosis has usually been performed via Sanger sequencing of a limited number of candidate genes. High-throughput sequencing is revolutionizin...

Journal: :The Journal of the Association of Physicians of India 2010
S Chatterjee P S Karmakar P Ghosh A Ghosh

Subdural hematoma (SDH) is a rare complication of immune thrombocytopenic purpura (ITP) the incidence being around 2%. Although SDH usually occurs secondary to trauma, in bleeding disorders it may occur spontaneously. Here we report subdural hematoma in two uncommon settings, one patient with systemic sclerosis developing secondary ITP and consequently subdural hematoma and the other patient wi...

2015
Dilek Gürlek Gökçebay Ali Fettah İsmail Kırbaş Bahattin Tunç Namık Yaşar Özbek

Invasive fungal infections have turned out to be a significant cause of morbidity and mortality in pediatric patients with malignant disorders. Massive hemoptysis, a rare complication of invasive pulmonary aspergillosis, may threaten the lives of patients, usually during the resolution of neutropenia. In this report, we describe a patient with massive hemoptysis due to invasive pulmonary asperg...

Journal: :Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 2014
Francesco Celestino Cristian Verri Francesco De Carlo Savino Mauro Di Stasi

Acquired Hemophilia A (AHA) is a rare bleeding diathesis characterized by the development of autoantibodies against factor VIII (FVIII). About half of the cases are idiopathic and the other half are associated with autoimmune diseases, postpartum problems, infections, inflammatory bowel disease, drugs, lymphoproliferative disorders or solid tumors . AHA is associated with malignancies in 7-15% ...

2010
Peyman Eshghi Mitra Mahdavi-Mazdeh Mehran Karimi Mohammad Aghighi

INTRODUCTION Management of haemophilia and inherited bleeding disorders is a major challenge especially in developing countries, because of a shortage or absence of products, the cost and the infrastructural health problems. Development of local expertise which results in an improved outlook and reduction in mortality and morbidity in these countries can be helpful for advocators in other devel...

Journal: :Thrombosis and haemostasis 2006
Tongyao Liu Ciaran D Scallan George J Broze Susanna Patarroyo-White Glenn F Pierce Kirk W Johnson

Additional therapeutic options are needed for patients with bleeding disorders such as hemophilia A, hemophilia B, severe von Willebrand disease, and other rare factor deficiencies. A novel approach to improve coagulation in such clotting disorders has been identified that, parodoxically, involves heparinlike sulfated polysaccharides. Select molecules of this broad class are largely devoid of a...

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