We prove a related fixed point theorem for n mappings which arenot necessarily continuous in n fuzzy metric spaces using an implicit relationone of them is a sequentially compact fuzzy metric space which generalizeresults of Aliouche, et al. [2], Rao et al. [14] and [15].

We give some general results concerning the computation of the generalized Feng-Rao numbers of numerical semigroups. In the case of a numerical semigroup generated by an interval, a formula for the r Feng-Rao number is obtained.

We congratulate the author for this excellent article, which ooers important methods and ideas for inference on functional Magnetic Resonance (fMR) images, with particular application to identifying and testing for theories on working memory utilization. Developing statistical methodology for the analysis of fMR images is an exciting and challenging task, bringing together issues from diverse d...

OBJECTIVE Canagliflozin, a sodium glucose cotransporter (SGLT) 2 inhibitor, is also a low-potency SGLT1 inhibitor. This study tested the hypothesis that intestinal canagliflozin levels postdose are sufficiently high to transiently inhibit intestinal SGLT1, thereby delaying intestinal glucose absorption. RESEARCH DESIGN AND METHODS This two-period, crossover study evaluated effects of canaglif...

A fundamental issue in NMR spectroscopy is the estimation of parameters such as the Larmor frequencies of nuclei, J coupling constants, and relaxation rates. The Cramer-Rao lower bound provides a method to assess the best achievable accuracy of parameter estimates resulting from an unbiased estimation procedure. We show how the Cramer-Rao lower bound can be calculated for data obtained from mul...

The performance of Kalman filter depends directly on the noise covariances, which are usually not known and need to be estimated. Several estimation algorithms have been published in past decades, but the measure of estimation quality is missing. The Cramér-Rao bounds represent limitation of quality of parameter estimation that can be obtained from given data. In this article, The Cramér-Rao bo...

BACKGROUND Patient-reported outcomes (PRO) that comprise all self-reported measures by the patient are important as endpoint in clinical trials and epidemiological studies. Models from the Item Response Theory (IRT) are increasingly used to analyze these particular outcomes that bring into play a latent variable as these outcomes cannot be directly observed. Preliminary developments have been p...

Secretoglobin family 1A member 1 (SCGB 1A1) is a small protein mainly secreted by mucosal epithelial cells of the lungs and uterus. SCGB 1A1, also known as club (Clara) cell secretory protein, represents a major constituent of airway surface fluid. The protein has anti-inflammatory properties, and its concentration is reduced in equine recurrent airway obstruction (RAO) and human asthma. RAO is...

The immunosuppressive effect of rapamycin is mediated by inhibition of interleukin-2-stimulated T cell proliferation. We report for the first time that rapamycin also inhibits growth factor-induced proliferation of cultured mouse proximal tubular (MPT; IC(50) ~1 ng/ml) cells and promotes apoptosis of these cells by impairing the survival effects of the same growth factors. On the basis of these...

The fist documented speculations on light were found in oriental and Greek schools of philosophy. investigations the India rooted way back to ancient era. Indian Samkhya, Nyaya, Vaisheshika identified or fie (Tejas) as one key elements among elementary things universe. pioneering results optics spectroscopy witnessed era stellar people like Sir Jagadish Chandra Bose C V Raman. research has then...