Rolling-circle amplification (RCA) and ramification amplification (RAM, also known as hyperbranched RCA) are isothermal nucleic acid amplification technologies that have gained a great application in in situ signal amplification, DNA and protein microarray assays, single nucleotide polymorphism detection, as well as clinical diagnosis. Real-time detection of RCA or RAM products has been a chall...

We train a number of neural networks to play games Bowling, Breakout and Seaquest using information stored in the memory of a video game console Atari 2600. We consider four models of neural networks which differ in size and architecture: two networks which use only information contained in the RAM and two mixed networks which use both information in the RAM and information from the screen. As ...

The 7-methylguanosine cap added to the 5' end of mRNA is required for efficient gene expression in eukaryotes. In mammals, methylation of the guanosine cap is catalyzed by RNMT (RNA guanine-7 methyltransferase), an enzyme previously thought to function as a monomer. We have identified an obligate component of the mammalian cap methyltransferase, RAM (RNMT-Activating Mini protein)/Fam103a1, a pr...

This paper provides an exploration of the concept and content of Agile Manufacturing. It describes the nature of the content of AM and synthesises the literature to propose a comprehensive definition of purpose and process. Real Agile Manufacturing (RAM) is viewed as a strategic process; it is about surviving and prospering in the competitive environment of continuous and unpredictable change b...

The effects of residual amplitude modulation (RAM) in laser interferometers using heterodyne sensing can be substantial and difficult to mitigate. In this work, we analyze the effects of RAM on a complex laser interferometer used for gravitational wave detection. The RAM introduces unwanted offsets in the cavity length signals and thereby shifts the operating point of the optical cavities from ...

A model for comparing resistance to Salmonella Enteritidis was evaluated in different broiler breeds. The recruitment and phagocytic activity of peritoneal macrophages were assessed in three different broiler breeds (A, B and C) which are farmed world-wide. Assessment was performed after three days of intraperitoneal (i.p.) administration of 3% Sephadex G-200 (10 ml), initiated at twenty-one da...