Lung cancer occurs in subjects with no history of active smoking in 15–25% of all cases, mainly females. Lung cancer in never-smokers is a recent field of investigation, with differences in clinical, pathological and molecular aspects compared with lung cancer in smokers [1, 2]. Chronic exposure to radon and its decay products is recognised as the second leading cause of lung cancer, after acti...

results significantly high levels of radon gas were found mostly in water and residential buildings. conclusions it conclusion with regard to the study of building materials, granite stone and adobe coverings cannot be recommended for construction purposes. materials and methods the most important route of exposure to such radiation is indoor places. in this investigation measurement of radon i...

A biodosimetric approach to determine alpha-particle dose to the respiratory tract epithelium from known exposures to radon has been developed in the rat. Cytotoxicity assays have been used to obtain dose-conversion factors for cumulative exposures typical of those encountered by underground uranium miners. However, this approach is not sensitive enough to derive dose-conversion factors for ind...

This work is devoted to studying the alpha activity distribution of natural radionuclides in boarding schools located near zones tectonic faults. There are many faults Almaty and this basis for referring southern capital Kazakhstan radon-hazardous territories. As a result radiometric measurements 2D-topology alpha-radiation flux density from distance fault was found. Based on results coefficien...

Radon risks derive from exposure of bronchio-epithelial cells to alpha particles. Alpha-particle exposure can result in bystander effects when irradiated cells emit signals resulting in damage to nearby unirradiated bystander cells. Bystander effects can cause downwardly-curving dose-response relations and inverse dose-rate effects. We have extended a quantitative mechanistic model of bystander...

Radon and its progenies have been ranked second of being responsible for lung cancer in humans. Hong Kong has four major groups of uranium-rich plutonic and volcanic rocks and is suffering from radon emanated therefrom. However, there is a lack of radon potential maps in Hong Kong to resolve the spatial distribution of radonprone areas. A ten-point radon potential system was developed in German...

To calculate the absorbed dose in the human lung due to inhaled radon progeny, ICRP focussed on the layers containing the target cells, i.e., the basal and secretory cells. Such an approach did not consider details of the sensitive cells in the layers. The present work uses the microdosimetric approach and determines the absorbed alpha-particle energy in non-spherical nuclei of target cells (ba...