BACKGROUND Stereotactic radiosurgery uses a single fraction high dose radiation while stereotactic radiotherapy uses multifractionated lower dose focused radiation. MATERIALS AND METHODS Radiosurgery used rigid CRW head frame while stereotactic radiotherapy utilized GTC or HNL relocatable frames. Stereotactic planning and radiation involved Radionics X-plan and LINAC system. RESULTS Since D...

Background Delivering training to participating sites is an essential part of successful trial setup especially when new techniques, treatments or technologies are involved. RAIDER is a multicentre (> 30 NHS Trusts) phase II trial of complex radiotherapy for muscle invasive bladder cancer. The radiotherapy techniques were developed at a single UK NHS site and in addition to written materials id...

For pathological high-risk prostate cancer, adjuvant irradiation has shown a survival benefit. Phase III studies have highlighted that half men would face biochemical relapse and would be candidate for radiotherapy at adjuvant or salvage times. Despite at least four published international contouring guidelines from different collaborative groups, discrepancies remain for volumes, delineation, ...

Introduction: Today different uses of multileaf collimators(MLC) in different techniques of radiotherapy are common. Due to the use of this facility it is possible to have maximum radiation dose to target volumes and minimum radiation dose to critical tissues surronding treatment volumes. But there are numerouse Linear accelerators in IRAN without MLC. Because of high price of...

Background: The present study aimed to introduce a rapid transmission dosimetry through an electronic portal-imaging device (EPID) to achieve two-dimensional (2D) dose distribution for homogenous environments. Material and Methods: In this Phantom study, first, the EPID calibration curve and correction coefficients for field size were obtained from EPID and ionization chamber. Second, the...

Radiotherapy for esophageal cancer relies on cross-sectional imaging to identify the entire extent of tumor. Rarely, the exact limits of the tumor may be radiologically occult. Lipiodol is a contrast agent which has been used successfully to mark cancers of the bladder and lung for radiotherapy and surgical resection. We report a patient with an adenocarcinoma of the gastroesophageal junction w...

OBJECTIVES In pediatric radiotherapy, the enhanced radiosensitivity of the developing tissues combined with the high overall survival, raise the possibility of late complications. The present study aims at comparing two dimensional (2D) and three dimensional (3D) planning regarding dose homogeneity within target volume and dose to organs at risk (OARs) to demonstrate the efficacy of 3D in decre...

The Monte Carlo (MC) method has been shown through many research studies to calculate accurate dose distributions for clinical radiotherapy, particularly in heterogeneous patient tissues where the effects of electron transport cannot be accurately handled with conventional, deterministic dose algorithms. Despite its proven accuracy and the potential for improved dose distributions to influence ...

DNA measurements on biopsy material from 24 squamous cell carcinomas of the oral cavity given preoperative radiotherapy indicate that DNA aneuploid tumours respond better to radiotherapy than do diploid and polyploid tumours. The mean S-phase value was higher (16.1%) for 8 tumours that were eradicated by preoperative radiotherapy than for 13 that did not respond (8.1%). These factors correlated...

The Radiotherapy Optimisation Test Set (TROTS) is an extensive set of problems originating from radiotherapy (radiation therapy) treatment planning. This dataset is created for 2 purposes: (1) to supply a large-scale dense dataset to measure performance and quality of mathematical solvers, and (2) to supply a dataset to investigate the multi-criteria optimisation and decision-making nature of t...