In this paper we report our investigations on the frequency stabilization and frequency measurements of 543 nm HeNe laser. It contains following four di€erent works. (1) Using a metal laser tube we have built an iodine-stabilized 543 nm HeNe laser by the Frequency-Modulation (FM) spectroscopy. The signal-to-noise ratio of the hyper®ne spectrum reached 2 ́ 10 at 1 s sampling time. (2) We have bu...

Multiple myeloma is a disseminated neoplasm of terminally differentiated plasma cells that is incurable with currently available therapies. Although the disease is radiosensitive, external beam radiation leads to significant toxicity due to sensitive end-organ damage. Thus, genetic approaches for therapy are required. We hypothesized that the incorporation of immunoglobulin promoter and enhance...

Isotope Exchange/Depth Profiling (IEDP) using Secondary Ion Mass Spectrometry (SIMS) has been used to determine the oxygen tracer diffusion and surface exchange coefficients of (100) oriented 9.5 mol% yttria stabilised zirconia single crystals. Exchange experiments performed with molecular oxygen are compared with the exchange using an oxygen plasma. The surface exchange coefficient for specime...

Radioactive iodine (1311) has a part to play in the therapy of two thyroid disorders, carcinoma and thyrotoxicosis, by virtue of the selective concentration of it which occurs in functioning thyroid cells. The latter represent the only significant site of concentration of the iodide ion in the body, this occurring because of the necessity to incorporate iodine into the molecule of the thyroid h...

Bronchoalveolar lavage (BAL) was performed on 11 atopic patients with mild asymptomatic bronchial asthma and 11 healthy nonasthmatic volunteers. All asthmatic subjects had evidence of bronchial hyperresponsiveness to inhaled carbachol. The concentrations of leukotriene (LT) C4, LTD4, LTE4, LTB4, prostaglandin D2 (PGD2), platelet-activating factor (PAF) and histamine in BAL fluid measured. The l...

Correct staging of prostate cancer is an unmet clinical need. Radionuclide targeting of prostate-specific membrane antigen (PSMA) with 111In-labeled capromab pendetide (ProstaScint) is a clinical option for prostate cancer staging. We propose the use of 124I-labeled capromab to decrease the retention of radioactivity in healthy organs (due to the non-residualizing properties of the radiolabel)....

BACKGROUND Measurement of radioactive iodine uptake (RAIU) is an important aspect of the assessment and treatment of patients with hyperthyroidism. Its uncertainty affects how much of a true change in RAIU can be detected as well as appropriateness of the therapy dosage upon which it is based. In this study, a method of estimating the reproducibility and least significant change (LSC) values fo...

Materials with apatite crystal structure have a great potential for incorporating the long-lived radioactive iodine isotope (129I) in the form of iodide (I) from nuclear waste streams. Because of its durability and potentially high iodine content, the apatite waste form can reduce iodine release rate and minimize the waste volume. Crystal structure and composition of apatite (A5(XO4)3Z) was inv...

background: the aim of the study was to evaluate the third trimester urinary iodine excretion and to assess its relation with newborns thyroid function. materials and methods: a total  of  208 healthy third trimester pregnant women without previous history of thyroid disease were included in the study. urinary iodine levels of mothers were measured and neonatal tsh levels were screened on the 3...

background: goiter is thyroid enlargement, which is the most common visible symptom of iodine deficiency. some studies have shown iodine deficiency in water, soil, and food in many places worldwide. we aimed to determine the prevalence of goiter and the association between urine iodine levels in children with severity and prevalence of goiter in mountainous villages of kashan city (center of ir...