Proton radiation for cancer offers the ability to conform the high-dose region of radiation therapy to the tumor while reducing the dose of radiation to adjacent normal tissues. In lung cancer, this equates to greater sparing of uninvolved lung, heart, esophagus, and spinal cord. Sparing these normal tissues permits the delivery of higher-radiation doses to the tumor. Studies that compare the d...

human body consists of some tissues among which bone is one of the important living and growing tissue . in this research, energy absorption buildup factor (eabf) values of 27 types of bone have been computed for photon energy 0.03 to 1.5 mev up to 40 mean free path (40mfp) penetration depths. the inner bone tissue, spongiosa and male sternum had the largest values of eabf in low photon energie...

BACKGROUND Tissue expanders are used in breast reconstruction after mastectomy to stretch the remaining tissue to create space for placement of permanent breast implants. The AeroForm™ Tissue Expander, developed by AirXpanders™ Inc., contains electronic components designed to activate the release of carbon dioxide from an internal reservoir to inflate the expander. Breast cancer patients who un...

Antiangiogenic therapy can enhance radiation-induced tumor growth inhibition. However, the effects of combined antiangiogenic and radiation therapy on long-term tumor control and normal tissue response have not been reported. We treated mice bearing two different human tumor xenografts with anti-vascular endothelial growth factor receptor-2 antibody (DC101) and five dose fractions of local radi...

In this paper, we present a real-time simulation and visualization framework that models a deformable surface lung model with tumor, simulates the tumor motion and predicts the amount of radiation doses that would be deposited in the moving lung tumor during the actual delivery of radiation. The model takes as input a subject-specific 4D Computed Tomography (4D CT) of lungs and computes a defor...

This case report describes a long follow-up of a patient treated for lung cancer by local therapy only using surgery and multiple radiation applications. Categories: Radiation Oncology

Clivus is a rare location for metastasis. We report patient with lung cancer presented to us diplopia and headache. He was found have clival metastasis treated palliative radiation therapy clivus. Metastasis also differential be considered when patients present lesion.

BACKGROUND For patients with sarcomas, radiotherapy can be used as neoadjuvant, adjuvant, or primary local therapy, depending on the site and type of sarcoma, the surgical approach, and the efficacy of chemotherapy. METHODS The authors review the current status of advanced technology radiation therapy in the management of bone and soft tissue sarcoma. RESULTS Advances in radiotherapy have r...

Background Radiotherapy is a mainstay for the treatment of lung cancer that can induce pneumonitis or pulmonary fibrosis. The matricellular protein connective tissue growth factor (CTGF) is a central mediator of tissue remodeling. Methods A radiation-induced mouse model of pulmonary fibrosis was used to determine if transient administration of a human antibody to CTGF (FG-3019) started at dif...

Four-dimensional volumetric modulated arc therapy (4D VMAT) is a treatment strategy for lung cancers that aims to exploit relative target and tissue motion to improve organ at risk (OAR) sparing. The algorithm incorporates the entire patient respiratory cycle using 4D CT data into the optimization process. Resulting treatment plans synchronize the delivery of each beam aperture to a specific ph...