TOPIC Attachment theory and reactive attachment disorder (RAD). PURPOSE To highlight current perspectives on attachment theory, RAD, and treatment implications using a case study of an 8-year-old patient with RAD. SOURCES Selected multidisciplinary literature related to attachment theory and RAD. CONCLUSIONS The literature provides a body of work that substantiates the importance of early...

Employment or Leadership: None declared. Consultant or Advisory Role: None declared. Stock Ownership: None declared. Honoraria: None declared. Research Funding: Bio-Rad Laboratories, ddPCR Reagents, Life Technologies, Acrometrix inhibition panel; K.R. Jerome, Bio-Rad Laboratories. Expert Testimony: None declared. Patents: None declared. Other Remuneration: T.C. Dingle, Bio-Rad Laboratories prov...

The role of mitochondria within injured neurons is an area of active interest since these organelles are vital for the production of cellular energy in the form of ATP. Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo, we surveyed genes related to mitochondrial function for effects on axon regrowth after laser axotomy. Genes ...

BACKGROUND Little is known about the specific reasons for antipsychotic discontinuation or continuation from patients' or clinicians' perspectives. This study aimed to assess the construct validity of 2 new measures of the Reasons for Antipsychotic Discontinuation/Continuation (RAD): RAD-I (a structured interview assessing the patient's perspective) and RAD-Q (a questionnaire assessing the clin...

Synchrotron radiation from active galactic nuclei (AGN) is often highly polarized. We present a search for linear polarization with the Very Large Array (VLA) at 4.8 GHz and 8.4 GHz from the nearest AGN, Sagittarius A*. As a part of this study we used spectro-polarimetric data that were sensitive to a rotation measure (RM) as large as 3:5 10 6 rad m ?2 at 4.8 GHz and 1:5 10 7 rad m ?2 at 8.4 GH...

The micromechanical properties of spider air flow hair sensilla (trichobothria) were characterized with nanometre resolution using surface force spectroscopy (SFS) under conditions of different constant deflection angular velocities theta (rad s(-1)) for hairs 900-950 microm long prior to shortening for measurement purposes. In the range of angular velocities examined (4 x 10(-4) - 2.6 x 10(-1)...

BACKGROUND In response to genotoxic stress, cells activate checkpoint pathways that lead to a transient cell cycle arrest that allows for DNA repair or to apoptosis, which triggers the demise of genetically damaged cells. RESULTS During positional cloning of the C. elegans rad-5 DNA damage checkpoint gene, we found, surprisingly, that rad-5(mn159) is allelic with clk-2(qm37), a mutant previou...