OBJECTIVE The aim of this study is to validate the Adult ADHD Self-Report Scale (ASRS) and Adult ADHD Investigator Symptom Rating Scale (AISRS) expanded versions, including executive function deficits (EFDs) and emotional dyscontrol (EC) items, and to present ASRS and AISRS pilot normative data. METHOD Two patient samples (referred and primary care physician [PCP] controls) were pooled togeth...

the urgent need of neuraminidase inhibitors (ni) has provided an impetus for understanding the structure requisite at molecular level. our search for selective inhibitors of neuraminidase has led to the identification of pharmacophoric requirements at various positions around acyl thiourea pharmacophore. the main objective of present study is to develop selective ni, with least toxicity and dru...

The rack is increasingly replacing individual servers as the basic building block of modern data centers. Future rack-scale computers will comprise a large number of tightly integrated systems-on-chip, interconnected by a switch-less internal fabric. This design enables thousands of cores per rack and provides high bandwidth for rack-scale applications. Most of the benefits promised by these ne...

High power dissipation from microprocessors, support chips, memory chips and mass storage has resulted in large overall power dissipation from computer systems. The deployment of these computer systems in large numbers and in very dense configurations in a data center has resulted in very high power densities at room level. These computer systems are deployed in a rack. A standard 2-meter high ...

UNLABELLED The purpose of this report is to describe an initial version of the Apraxia of Speech Rating Scale (ASRS), a scale designed to quantify the presence or absence, relative frequency, and severity of characteristics frequently associated with apraxia of speech (AOS). In this paper we report intra-judge and inter-judge reliability, as well as indices of validity, for the ASRS which was c...

The purpose of this communication is to describe a rack which permits the simultaneous handling of 24 culture vials for purposes of plaque assays of viruses, interferon assays, cloning of cells, and other related procedures in cell culture. In this laboratory, the rack has been found to decrease significantly the time and effort required for the manipulation of moderate to large numbers of cult...

With great advances in the field of in vitro brain modelling, the challenge is now to implement these technologies for development and evaluation of new drug candidates. Here we demonstrate a method for culturing three-dimensional networks of spontaneously active neurons and supporting glial cells in a microfluidic platform. The high-throughput nature of the platform in combination with its com...

Distribution Extents (DE) of order k for a sample {x1, x2,... xn} of a non-negative stochastic variable X can be defined as