The Haemophilus influenzae P4 lipoprotein (hel) is a potential component of a nontypeable H. influenzae otitis media vaccine. Since P4 is known to be an enzyme, nonenzymatically active forms of recombinant P4 are required. After site-directed mutagenesis of the hel gene, three of the mutated proteins were shown to be vaccine candidates.

RespirologyVolume 26, Issue S3 p. 153-153 AbstractFree Access P4-26: Withdrawn First published: 19 November 2021 https://doi.org/10.1111/resp.14150_201AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version article.I have read accept the Wiley O...

Organelle damage and increases in mitochondrial permeabilization are key events in the development of cerebral ischemic tissue injury because they cause both modifications in ATP turnover and cellular apoptosis/necrosis. Early restoration of blood flow and improvement of mitochondrial function might reverse the situation and help in recovery following an onset of stroke. Mitochondria and relate...

Vitamin E (Vit. E) is needed for young rabbits to prevent reproductive abnormalities, abortion and poor survivability of kits. Also, exogenous progesterone (P4) is needed for rabbits to enhance early embryonic development because of inadequate corpus luteum (CL) development at this age. Hence, the aim of this study was to investigate the effect of injecting Vit. E and the combination Vit. E+P4 ...

The foundational elements of cells and tissues are water, lipid, protein, mineral, vitamins, carbohydrates. A healthy varied diet, fortified food & nutraceuticals that provide appropriate macro micronutrients required to maintain functioning wear tear the human body. Nutraceuticals (Nutrition + pharmaceuticals) isolated nutrients or dietary supplements medical health benefits, including prevent...

The P4-sparse Graph Sandwich Problem asks, given two graphs G 1 = (V, E1) and G2 = (V, E2), whether there exists a graph G = (V, E) such that E1 ⊆ E ⊆ E2 and G is P4-sparse. In this paper we present a polynomial-time algorithm for solving the Graph Sandwich Problem for P4-sparse graphs. c © 2008 Elsevier B.V. All rights reserved.

Michael Glick, DMD P revention, health screening, and assessing risk are concepts that lie at the core of medicine and dentistry and affect how all of us practice. In order to apply these concepts effectively, we must be clear in defining them. Prevention can be separated into primary, secondary, tertiary, and quaternary prevention. Primary prevention usually refers to an attempt to reduce a cl...

The objectives of this study were to determine the effects of dose of exogenous progesterone (P4) prior to artificial insemination on concentrations of 17 beta-estradiol (E2) and on conception rates in bovine females. Heifers (n = 100) and cows (n = 100) received P4-releasing intravaginal devices (PRIDs) to produce two different circulating concentrations of P4. All animals received a single PR...

1. We have studied the metabolism of Ins(1,3,4,5)P4 (inositol 1,3,4,5-tetrakisphosphate) by rat liver homogenates incubated in a medium resembling intracellular ionic strength and pH. 2. Ins(1,3,4,5)P4 was dephosphorylated to a single inositol trisphosphate product, Ins(1,3,4)P3 (inositol 1,3,4-trisphosphate), the identity of which was confirmed by periodate degradation, followed by reduction a...