نتایج جستجو برای: qtc prolongation

تعداد نتایج: 11103  

Journal: :Pakistan Journal of Medical and Health Sciences 2022

Objective: To find out the frequency of corrected QT interval (QTc) prolongation in patients with liver cirrhosis. Study Design: Cross-sectional study. Place and Duration: The department medicine, “Aziz Bhatti Shaheed Teaching Hospital”, Gujrat from April 2021 to October 2021. Methodology: A total 150 both genders aged 18-65 years having cirrhosis were included. Proper medical history clinical ...

Journal: :Journal of the American College of Cardiology 2004
Jacqueline M Dekker Richard S Crow Peter J Hannan Evert G Schouten Aaron R Folsom

OBJECTIVES We aimed to study the predictive value of heart rate-corrected QT interval (QTc) for incident coronary heart disease (CHD) and cardiovascular disease (CVD) mortality in the black and white general population, and to validate various QT measurements. BACKGROUND QTc prolongation is associated with higher risk of mortality in cardiac patients and in the general population. Little is k...

Journal: :Anesthesiology 2008
Beny Charbit Jean Claude Alvarez Eric Dasque Emuri Abe Jean Louis Démolis Christian Funck-Brentano

BACKGROUND Droperidol and ondansetron have previously been found to prolong the QT interval in the treatment of postoperative nausea and vomiting. However, this adverse effect has never been confirmed and compared with both drugs under controlled conditions. The objective was to study the effects of droperidol and ondansetron alone or in combination on QT interval duration in healthy subjects. ...

Journal: :Progress in Pediatric Cardiology 2021

Prolongation of the ECG derived QT interval predicts increased risk for sudden life-threatening arrhythmias. Many medicines are known to prolong though current data demonstrate that progesterone given premenopausal females <18 years shortens by six msec. This effect may be used treat individuals with abnormal prolongation interval. Hormone progestin is a number conditions in post-menarche >18 o...

2011
Tristan M. Sissung Erin R. Gardner Richard L. Piekarz Reuben Howden Xiaohong Chen Sukyung Woo Ryan Franke James A. Clark Laura Miller-DeGraff Seth M. Steinberg David Venzon David Liewehr Steven R. Kleeberger Susan E. Bates Douglas K. Price Douglas R. Rosing Christopher Cabell Alex Sparreboom William D. Figg

Purpose: Although the ABCB1 (P-glycoprotein) drug transporter is a constituent of several blood–tissue barriers (i.e., blood–brain and blood–nerve), its participation in a putative blood–heart barrier has been poorly explored. ABCB1 could decrease the intracardiac concentrations of drugs that cause QT prolongation and cardiotoxicity. Experimental Design: ABCB1-related romidepsin transport kinet...

Journal: :The American journal of cardiology 2011
R Thomas Collins

Williams syndrome (WS) is a congenital developmental disorder affecting the connective tissue, neurologic, and cardiovascular (CV) systems in 1 in 8,000 live births. The characteristic features of WS, including facial dysmorphisms, cognitive traits, and CV abnormalities, are known to arise from the deletion of approximately 28 genes on chromosome 7q11.23. Structural CV abnormalities occur most ...

Journal: :acta medica iranica 0
asadolah alidoosti department of radiation oncology, imam hossein hospital, shaheed beheshti univesity of medical sciences, tehran, iran. farnaz taslimi department of radiation oncology, imam hossein hospital, shaheed beheshti univesity of medical sciences, tehran, iran. ahmad ameri department of radiation oncology, imam hossein hospital, shaheed beheshti univesity of medical sciences, tehran, iran. majir sheibani khosro department of radiation oncology, imam hossein hospital, shaheed beheshti univesity of medical sciences, tehran, iran. reza miri department of radiation oncology, imam hossein hospital, shaheed beheshti univesity of medical sciences, tehran, iran. parvin yavari department of radiation oncology, imam hossein hospital, shaheed beheshti univesity of medical sciences, tehran, iran.

cancer patient receive various cytotoxic drugs in association with antiemetic drugs such as 5ht3 receptor antagonists as their chemotherapy regimen. 5ht3 receptor antagonists have been reported to produce changes in ecg parameter. there are only a few studies about cardiovascular events of these drugs in patient receiving potentially cardiotoxic chemotherapies. the subject of this study is to e...

2017
Sanmoy Karmakar Md Asif Ali Rammohan Bera Hindol Mazumdar Tuhinadri Sen

Drugs with low arrhythmogenic tendencies fail to overcome the threshold to prolong QT interval and are ruled as safe. However, at provoked conditions these drugs might have the possibility to precipitate arrhythmia. Although small yet QT prolongation capability of such drugs must be investigated. The threshold required to prolong QT was attenuated using chronic dose of furosemide and clarithrom...

Journal: :Circulation journal : official journal of the Japanese Circulation Society 2007
Tsung-Hsien Lin Herng-Chia Chiu Ho-Ming Su Suh-Hang Hank Juo Ya-Ting Lee Wen-Chol Voon Wen-Ter Lai Sheng-Hsiung Sheu

BACKGROUND There has not been a longitudinal investigation of the influence of angiotensin-converting enzyme (ACE) insertion/deletion and angiotensinogen (AGT) M235T gene polymorphisms on repolarization parameters, such as QT dispersion (QTd) and the peak and the end of the T-wave interval (Tpe). METHODS AND RESULTS Electrocardiographys were recorded from 106 elderly Chinese at baseline, and ...

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