The chemotherapeutic agent known as 5-fluorouracil (5-FU) is an artificial fluoropyrimidine antimetabolite that has been widely used for its antineoplastic properties. Cocrystals of with five different Schiff bases (benzylidene-urea (BU), benzylidene-aniline (BA), salicylidene-aniline (SA), salicylidene-phenylhydrazine (SPH), and para-hydroxy benzylideneaniline (HBA)) are reported in this study...

In this investigation, three new crystal forms of lidocaine, and another lidocaine hydrochloride with hydroquinone, resorcinol, pyrogallol were synthetised. All the characterised using multiple techniques, PXRD, SC-XRD, DSC, FTIR. The stability was studied, and, for more stable forms, i.e., (lidhcl) solubility determined through FTIR analysis. crystalline obtained coformers showed an interestin...

In this work, we studied the optimization of synthetic approaches to creating structurally modified metal-organic frameworks under various synthesis conditions. We investigated influence solvents and zinc salts on structural characteristics framework based benzene-1,3,5-tricarboxylic acid (H3BTC). The results indicate that variation types both solvent salt is a parameter affecting crystallinity...

nanostructured ruo2 powders were synthesized via a hydrothermal method at 180 °c for 12 h using 1 and 2 m naoh aqueous solutions. the structure of the obtained nanomaterials was investigated by powder x-ray diffraction (pxrd) technique. the morphology the obtained materials were studied by field emission scanning electron microscope (fesem). the technique showed that with changing the reaction ...

One new coordination polymer, namely, [Cd3(H2L)3(Pza)2(H2O)2]n (1) was synthesized by the reaction of Cd(NO3)2·4H2O with 1,4-di(1H-imidazol-4-yl)benzene (H2L) and 3,5-pyrazoledicarboxylic acid (H3pza) and characterized by single-crystal X-ray diffraction, IR spectroscopy, elemental analysis, and powder X-ray diffraction (PXRD). The H3pza ligand was completely deprotonated to pza3−, which bridge...

The self-assembly of non-ionic amphiphiles with a hydroxylated oxanorbornane head-group was controlled using amino acid units as spacers between hydrophilic and lipophilic domains to get spherical supramolecular aggregates. The ability of these systems to harbour therapeutic agents like ibuprofen, and their drug-release profiles were evaluated. Apart from directing the assembly, the intervening...

A new complex, [Cu4(HL)4(H2O)14] (1, H3L·HCl = 5-((4-carboxypiperidin-1-yl)methyl) isophthalic acid hydrochloride), has been prepared and characterized by single-crystal X-ray diffraction, elemental analysis, IR spectroscopy and powder X-ray diffraction (PXRD). The result of the X-ray diffraction analysis reveals that the complex crystallizes in monoclinic, space group C2/c and three unique Cu(...

The objective of this study was to improve the stability and water-solubility of patchouli alcohol by complexing with β-cyclodextrin (β-CD). The interactions between patchouli alcohol and β-CD were characterized by differential scanning calorimetry (DSC), Fourier transformation-infrared (FT-IR) spectroscopy, powder X-ray diffraction (PXRD), and Scanning electron microscope (SEM), respectively. ...

An immobilized copper Schiff base tridentate complex was prepared in three steps from SBA-15 supports. The immobilized copper nanocatalyst (heterogeneous catalyst) was characterized by Fourier transform infrared spectroscopy (FT-IR), cross polarization magic angle spinning (CP-MAS), 13-carbon nuclear magnetic resonance (13C-NMR), atomic absorption spectroscopy (AAS), thermogravimetric analysis ...

Chondroitin sulfate and sodium alginate were incorporated in different ratios to prepare glutaraldehyde (GA) crosslinked microspheres by water-in-oil emulsion crosslinking method for delivery of 5-flurouracil (5-FU) to colon. Chemical interaction, surface morphology, thermal degradability, crystallinity evaluation, elemental analysis and drug release results were computed by using FTIR, SEM, DS...