MOTIVATION To improve the detection of nucleotide sequence signals (e.g. promoter elements) by position-weight matrices (PWM) using the concept of statistically significant matches. RESULTS The Mksite program was originally developed for analyzing protein sequences. We report NMksite, a new version adapted to the processing of nucleotide sequences. NMksite creates PWM from nucleotide sequence...

This study was aimed to examine the role of iron in causing periventricular white matter (PWM) damage following a hypoxic injury in the developing brain. Along with iron, the expression of iron regulatory proteins (IRPs) and transferrin receptor (TfR), which are involved in iron acquisition, was also examined in the PWM by subjecting 1-d-old Wistar rats to hypoxia. Apart from an increase in iro...

This study aimed to show the difference of epilepsy from another chronic neurological disorder with episodic manifestations (CDEM): migraine. Seventy persons with epilepsy (PWE), 56 persons with migraine (PWM) and 45 healthy control participants (HCs) were included. The groups were compared in terms of demographics, quality of life, depression and self-esteem. The PWE and PWM were also compared...

The need for high power apparatus in industry has increased in recent years. Multilevel inverters have developed as easy alternatives for such power requirements. Multilevel inverters consist of a group of semiconductor switches and a set of voltage source components like capacitors or independent sources. The basic concept of these inverters depends on using this series of switches and sources...

It is well-known that rectifiers are used widely in many applications required AC/DC transformation. With technological advances, many studies are performed for AC/DC converters and many control methods are proposed in order to improve the performance of these rectifiers in recent years. Pulse width modulation (PWM) based rectifiers are one of the most popular rectifier types. PWM rectifiers ha...

The role of recombinant B cell stimulatory factor 2 (BSF-2/IL-6) in the regulation of growth and differentiation of B cells was investigated. rBSF-2 at 200 pg/ml could induce 50% of the maximum Ig production in B lymphoblastoid cell lines, the specific activity being estimated as 5 X 10(6) U/mg. rBSF-2 augmented PWM-induced IgM, IgG, and IgA production in mononuclear cells (MNC); the effect was...

In the present study, changes in the parahippocampal white matter (PWM), in the region that includes the perforant path, were investigated, in vivo, in 14 individuals with amnestic mild cognitive impairment (aMCI) compared to 14 elderly controls with no cognitive impairment (NCI). For this purpose, (1) volumetry; (2) diffusion tensor imaging (DTI) derived measures of mean diffusivity (MD) and f...

Multilevel voltage source inverter has been recognized as an important alternative to the normal two level voltage source inverter, especially in high power application. Using multilevel technique, the output voltage amplitude is increased, switching devices stress is reduced and the overall harmonics profile is improved. Three presentable topologies can b considered for multilevel inverter (ML...

During development, neural competence is conferred and maintained by integrating spatial and temporal regulations. The Drosophila sensory bristles that detect mechanical and chemical stimulations are arranged in stereotypical positions. The anterior wing margin (AWM) is arrayed with neuron-innervated sensory bristles, while posterior wing margin (PWM) bristles are non-innervated. We found that ...

This paper presents a new family of pulsewidthmodulated (PWM) converters, featuring soft commutation of the semiconductors at zero current (ZC) in the transistors and zero voltage (ZV) in the rectifiers. Besides operating at constant frequency and with reduced commutation losses, these new converters have output characteristics similar to the hard-switchingPWM counterpart, which means that ther...