Pure red cell aplasia (PRCA) is a rare hematologic disorder characterized by normocytic normochromic anemia with reticulocytopenia and depleted erythroid precursors. It reported mainly from western countries. We report our experience in two patients of PRCA India, the clinical characteristics, differential diagnosis, their management. Our showed improvements following treatment corticosteroids,...

Up to 1964 128 cases of congenital red cell aplasia had been reported (Table). All these were in Caucasian children and this was thought to be of genetic significance (Diamond, Allen, and Magill, 1961). Since then Khatua (1964) has described an 18-month-old Indian girl with red cell aplasia, whose chest radiograph showed an enlarged thymus gland, and who responded to steroids, while Shapiro, Wh...

AIM To define the relation between T large granular lymphocyte (T-LGL) leukaemia and pure red cell aplasia in Chinese patients. METHODS Patients with T-LGL leukaemia were identified from a consecutive series of Chinese patients with chronic lymphoproliferative disorders. The diagnosis of T-LGL leukaemia was based on typical morphological and immunophenotypical features, and confirmed by the d...