نتایج جستجو برای: puma
تعداد نتایج: 2161 فیلتر نتایج به سال:
Data is about the mitochondrial apoptosis regulatory framework genes PUMA, DRP1 (apoptotic), and ARC (anti-apoptotic) analysis after the employment of their controlling miRNAs inhibitors. The data represents putative conserved targeting of seed regions of miR-15a, miR-29a, and miR-214 with respective target genes PUMA, DRP1, and ARC. Data is of cross interference in expression levels of one miR...
In response to DNA damage, the p53 tumor suppressor can elicit either apoptosis or cell-cycle arrest and repair, but how this critical decision is made in specific cell types remains largely undefined. We investigated the mechanism by which the transcriptional repressor Slug specifically rescues hematopoietic progenitor cells from lethal doses of gamma radiation. We show that Slug is transcript...
The Chk2-p53-PUMA pathway is a major regulator of DNA-damage-induced apoptosis in response to double-strand breaks in vivo. Through analysis of 53BP1 complexes we have discovered a new ubiquitin protease, USP28, which regulates this pathway. Using a human cell line that faithfully recapitulated the Chk2-p53-PUMA pathway, we show that USP28 is required to stabilize Chk2 and 53BP1 in response to ...
A Mobile ad-hoc network is an autonomous system of mobile nodes connected by wireless links; each node operates as an end system and a router for all other nodes in the network. In each communication operation we use multicasting technique. In multicasting technique signified for group communication that supports the dissemination of information from a sender to all the receivers in a group whi...
Multicasting is a challenging task that facilitates group communication among the nodes using the most efficient strategy to deliver the messages over each link of the network. In spite of significant research achievements in recent years, efficient and extendable multicast routing in Mobile Ad Hoc Networks (MANETs) is still a difficult issue. This paper proposes the comparison of ODMR and PUMA...
The design of a 32-bit dual-issue 4-way super scalar PowerPC fixed point unit microprocessor tool research, in addition to being used for the analysis and development of circuit design techniques in SOI. (PUMA) in a 0.18mm TSMC process is described. The architectural details of the PUMA system are described. The design considerations and the implementation details are elaborated. This processor...
In response to DNA damage, the tumor suppressor p53 elicits a complex cellular response. In this issue of Cell, Wu et al. (2005) show that the transcription factor SLUG is induced by p53 and protects hematopoietic progenitor cells from apoptosis triggered by DNA damage. SLUG exerts this protective role by repressing Puma, a proapoptotic target of p53. PUMA is also a key coordinator of apoptosis...
To achieve long-term viability of hunted puma (Puma concolor) populations (even at historically low densities), we propose a management plan based on the metapopulation concept that designates source areas (closed to hunting) and sink areas (open to hunting). We use 11 years of data from Idaho and Utah to demonstrate how the proposed management plan might be implemented. We use minimum and maxi...
In this paper, principal-singular-vector utilization for modal analysis (PUMA) was adapted to perform time delay estimation on ground-penetrating radar (GPR) data by taking into account the shape of transmitted GPR signal. The super-resolution capability PUMA used separate overlapping backscattered echoes from a layered pavement structure with some embedded debondings. well-known root-MUSIC alg...
The commitment to programmed cell death via apoptosis is largely made upon activation of the proapoptotic mitochondrial proteins Bax or Bak. In this issue, Gallenne et al. (Gallenne, C., F. Gautier, L. Oliver, E. Hervouet, B. Noël, J.A. Hickman, O. Geneste, P.-F. Cartron, F.M. Vallette, S. Manon, and P. Juin. 2009. J. Cell Biol. 185:279-290) provide evidence that the p53 up-regulated modulator ...
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