Lower extremity transcutaneous oxygen tension (TcPO2) is used in diagnostic and prognostic indicator of tissue perfusion and is reduced in diabetes mellitus. Since cardiac output, leg blood flow and microvascular perfusion each can singly or jointly effect tissue oxygenation, the relative importance of macro- vs microvascular factors has not been resolved. To clarify this issue we compared TcPO...

The objective of the project was to study the influence of various hemodynamic and rheologic factors on the accuracy of 3-D power Doppler angiography (PDA) for quantifying the percentage of area reduction of a stenotic artery along its longitudinal axis. The study was performed with a 3-D power Doppler ultrasound (US) imaging system and an in vitro mock flow model containing a simulated artery ...

In this study, a patient-specific carotid artery model was analyzed with an open source program foam-extend. The research includes the effect of arterial wall deformation by fluid-structure analysis. Pulsatile velocity cycle is trained for 144 patients different hemodynamic parameters, machine learning algorithm using blood flow measured from 337 points artery. Data used training obtained in li...

Hypertension is a cardiovascular risk factor whose adverse effects have been attributed to a reduction in the calibre and/or number of small arteries and arterioles, resulting in increased peripheral vascular resistance. Peripheral vascular resistance and cardiac output are determinants of the mean blood pressure. These indices refer to steady-state phenomena, i.e. pressure and flow are conside...

This study looks at pulsatile blood flow through four different right coronary arteries, which have been reconstructed from biplane angiograms. A non-Newtonian blood model (the Generalised Power Law), as well as the usual Newtonian model of blood viscosity, is used to study the wall shear stress in each of these arteries over the entire cardiac cycle. The difference between Newtonian and non-Ne...

BACKGROUND Hemocompatibility is highly affected by the flow field in Left Ventricular Assistant Devices (LVAD). OBJECTIVE An asymmetric inflow and outflow channel arrangement with a 45° intersection angle with respect to the blood chamber is proposed to approximate the vascular structure of the aorta and left atrium on the left ventricle. The structure is expected to develop uninterruptible v...