OBJECTIVES This study was designed to assess the feasibility, efficacy and safety of mechanical fragmentation of pulmonary emboli using a new rotational pigtail catheter system. BACKGROUND Acute massive pulmonary embolism associated with right ventricular dysfunction is frequently lethal, despite high-dose thrombolytic therapy. Adjunctive catheter fragmentation may prevent a fatal outcome. ...

A transducer-tipped catheter with simultaneous frequency modulated electrocardiograms and a miniaturised tape recorder was used to record ambulatory pulmonary artery pressure for 24-48 hours in 19 men (mean age 57.7) with clinical and angiographic evidence of coronary artery disease. Sixty seven episodes of ST segment depression (greater than 1 mm) were recorded. Thirty five were accompanied by...

AIMS The study sought to assess the effect of percutaneous pulmonary artery denervation (PADN) on balloon-occlusion-induced acute pulmonary arterial hypertension (PAH) in vivo. The PADN is a minimally invasive and endovascular catheter-based interventional therapy using radiofrequency ablation to abolish the pulmonary arterial baroreceptors to pressure response. METHODS AND RESULTS To examine...

CASE DESCRIPTION 2 cats were examined because of congestive heart failure secondary to heartworm infection. CLINICAL FINDINGS One cat had severe abdominal distention and the other had dyspnea secondary to chylothorax. Both had loud right-sided heart murmurs, precordial thrills, and jugular distension. Thoracic radiography revealed cardiomegaly and enlarged caudal pulmonary arteries. Echocardi...

T HE object of this investigation was to measure simultaneous changes in blood pressure and blood flow in the pulmonary circulation of the intact dog. Observations were made during standing and running at different rates on a treadmill. A further group of dogs subjected recently to ligation and division of the left pulmonary artery was studied also. This permitted an extension of the observatio...

A 77-yr-old male was admitted for aortic aneurysm repair. His history recorded hypertension, left carotid artery desobstruction, stroke and an anterior invocardial infarction. Aspirin was discontinued 1 day before surgery. For periand postoperative haemodynamic surveillance, a Swan-Ganz catheter (7.5 Fr thermodilution catheter; Criticath; Ohmeda, Bilthoven, the Netherlands) was introduced throu...