During development, an increase in gonadotropin-releasing hormone (GnRH) release occurs that is critical for the initiation of puberty. This increase is attributable, at least in part, to activation of the GnRH neurosecretory system by inputs from neurotransmitters, such as glutamate, acting via NMDA receptors. We examined changes in GnRH and NMDA-R1 gene expression by RNase protection assay of...

BACKGROUND AND OBJECTIVE Studies of the relationship of weight status with timing of puberty in boys have been mixed. This study examined whether overweight and obesity are associated with differences in the timing of puberty in US boys. METHODS We reanalyzed recent community-based pubertal data from the American Academy of Pediatrics' Pediatric Research in Office Settings study in which trai...

INTRODUCTION Delayed pubertal maturation has been reported in girls with type 1 diabetes. OBJECTIVES To report the age of onset of puberty and menarche in girls with type 1 diabetes diagnosed before puberty. To investigate clinical factors affecting the occurrence of puberty and menarche in this population. PATIENTS AND METHODS A retrospective study of 38 girls with type 1 diabetes, all of ...

Abstract: Puberty is an important stage of human life. Several physiological alterations accompanying the teenage years manifest themselves in often complex and curious means to which females show different reactions. Even though this a female's life normal, it associated with some degree suffering embarrassment, mainly due sense hesitation. The main event puberty onset menstrual cycle; menstru...

OBJECTIVE To verify if the frequency of spontaneous pubertal development among girls with Turner syndrome (TS) diagnosed in infancy and childhood is greater than that of patients diagnosed later. SUBJECTS AND METHODS Thirty three girls aged < 10 years at the time of diagnosis were evaluated regarding pubertal development. The frequency of spontaneous puberty was compared with that of girls ag...

Puberty prepares mammals to sexually reproduce during adolescence. It is also hypothesized to invoke a social metamorphosis that prepares adolescents to take on adult social roles. We provide the first evidence to support this hypothesis in humans and show that pubertal development retunes the face-processing system from a caregiver bias to a peer bias. Prior to puberty, children exhibit enhanc...

The onset of puberty marks a time of rapid linear growth, sexual development, and transition from childhood to maturity. The diagnosis and treatment of a childhood malignancy prior to the onset of puberty has the potential to profoundly affect the timing and the tempo of puberty. CNS tumors located in the hypothalamic-pituitary (H-P) region, surgical resection in this location, and exposure to ...

My colleague Fridolf Kudlien in his recent paper "Empticius servus __ .n (Historia 35 [1986] p. 248) has remarked on the fact that in the ancient slave-market youth was at a premium. He points out that the manganes applied vegetable salves to arrest puberty and quotes Pliny N.H. XXI 170. The growth of pubic hair was arrested (N.H. XXX 41). The following Greeklarallels attest to the widespread b...

The objective of this trial was to determine the effect of age at first estrus on BW changes and long-term reproductive performance of sows. At approximately 100 d of age, prepubertal C22 gilts (n = 431) were allocated to trial. At a pen average of 140 d of age, gilts began daily direct contact with mature boars to stimulate onset of puberty. Gilts (n = 317, 73%) were recorded as cyclic by 180 ...