Progressive supranuclear palsy (PSP) has been reported as a disorder mainly characterized by tendency to fall, vertical gaze palsy, and constriction of the body axis, akinesia, cognitive impairment. Patients presenting with these typical clinical features are diagnosed having PSP-Richardson syndrome (PSP-RS). Electronystagmography (ENG) is useful for detection ocular motility disorder, which ma...

Larval pupation site preference (PSP) is an important event in preadult development. The PSP was studied on the basis of the number of larvae pupated at different sites in the cultures. The results revealed that the larval PSP in different species of Drosophila varies significantly at different sites. The sympatric species also differ in their PSP and the pupation behaviour does not correspond ...

OBJECTIVE To examine the potential utility of conventional MRI signs in differentiating pseudoprogression (PsP) from early progression (EP). METHODS This retrospective study reviewed initial postradiotherapy MRI scans of 321 patients with glioblastoma undergoing chemotherapy and radiotherapy. A total of 93 patients were found to have new or increased enhancing mass lesions, raising the possib...

Despite elevated incidence and recurrence rates for Primary Spontaneous Pneumothorax (PSP), little is known about its etiology, and the genetics of idiopathic PSP remains unexplored. To identify genetic variants contributing to sporadic PSP risk, we conducted the first PSP genome-wide association study. Two replicate pools of 92 Portuguese PSP cases and of 129 age- and sex-matched controls were...

BACKGROUND Trefoil peptides are secreted by mucus producing cells in the gastrointestinal tract and are supposed to be involved in oligomerisation processes of the mucin glycoproteins in the lumen. Endocrine functions have also been suggested. AIMS To target possible binding sites for iodine-125 labelled porcine spasmolytic polypeptide (pSP) in an in vivo rat model. METHODS 125I-pSP was giv...

In search of natural bioactive microbial compounds with adjuvant properties, we have previously showed that the polysaccharopeptide (PSP), isolated from Chinese medicinal mushroom Coriolus versicolor, was able to enhance the cytotoxicity of certain S-phase targeted-drugs on human leukemic HL-60 cells via some cell-cycle and apoptotic-dependent pathways. The present study aimed to investigate wh...

Progressive Supranuclear Palsy (PSP) is a rare and progressive movement disorder pathologically characterized by tau tangles for which there are no effective therapies. Emerging therapies for Alzheimer’s Disease are increasingly focus on tau and consequently, PSP has emerged as an attractive patient population in which to test novel tau-directed therapies. There are currently no approved therap...

The authors of this report present the history of primary spontaneous pneumothorax (PSP) treatment, its etiology, clinical symptoms, and diagnostic methodology. Further, they discuss minimally invasive methods of treating PSP such as thoracentesis and chemical pleurodesis. They discuss the pros and cons of each method, emphasizing that, according to the international recommendations, they shoul...

The Personal Software Process is a process improvement methodology aiming at individual software engineers. It claims to improve software quality (in particular defect content), effort estimation capability, and process adaptation and improvement capabilities. We have tested some of these claims in a controlled experiment comparing the performance of participants who had just previously receive...

The effect of follicle stimulating hormone (FSH) treatment on the pituitary response to gonadotrophin-releasing hormone (GnRH) was studied in rats in various reproductive conditions. A 3-day treatment of cycling rats with FSH (Metrodin; 10 IU/injection) lowered the spontaneous pre-ovulatory. LH-surge and suppressed the pituitary luteinizing hormone (LH) response to GnRH. FSH also suppressed the...