نتایج جستجو برای: proton pump inhibitors

تعداد نتایج: 298233  

Journal: :Pharmacotherapy 2003
Lynda S Welage

Since their introduction into clinical practice in the 1980s, proton pump inhibitors (PPIs) have proved to be of enormous value in the management of acid peptic disorders. They have become the treatment of choice for most, if not all, acid-related gastrointestinal disorders, including gastroesophageal reflux disease, peptic ulcer, and Zollinger-Ellison syndrome. With approval of an intravenous ...

2016
Floris Imhann Marc Jan Bonder Arnau Vich Vila Jingyuan Fu Zlatan Mujagic Lisa Vork Ettje F Tigchelaar Soesma A Jankipersadsing Maria Carmen Cenit Hermie J M Harmsen Gerard Dijkstra Lude Franke Ramnik J Xavier Daisy Jonkers Cisca Wijmenga Rinse K Weersma Alexandra Zhernakova

BACKGROUND AND AIMS Proton pump inhibitors (PPIs) are among the top 10 most widely used drugs in the world. PPI use has been associated with an increased risk of enteric infections, most notably Clostridium difficile. The gut microbiome plays an important role in enteric infections, by resisting or promoting colonisation by pathogens. In this study, we investigated the influence of PPI use on t...

2001
Masatsugu Shiba Kazunari Tominaga

1. Bronowicki JP, Venard V, Botte C, et al. Patient-to-patient transmission of hepatitis C virus during colonoscopy. N Engl J Med 1997;337:237–40. 2. Tytgat GNJ. Endscopic transmission of Helicobacter pylori. Aliment Pharmacol Ther 1995;9(suppl 2):105–10. 3. Yang R, Ng S, Nichol M, et al. A cost and performance evaluation of disposable and reusable biopsy forceps in GI endoscopy. Gastrointest E...

2011
David A. Peura

The prevalence of gastroesophageal reflux disease (GERD) continues to rise, placing an increasing burden on our health care system. Proton pump inhibitors (PPIs) are the most effective and widely used therapy for GERD. Many PPIs are now available in generic and over-the-counter forms, and managed care formularies often choose these as their preferred drug for GERD treatment. However, newer-gene...

Journal: :Current opinion in allergy and clinical immunology 2012
Yoon-Seok Chang

PURPOSE OF REVIEW Proton pump inhibitors (PPI) are one of most frequently prescribed drugs in the world. The purpose of this review is to describe the hypersensitivity reactions to PPI. RECENT FINDINGS Hypersensitivity reactions to PPI vary from mild symptoms to life-threatening disorders. Cases of urticaria, angioedema, anaphylaxis, cytopenia, vasculitis, acute allergic interstitial nephriti...

Pantoprazole is a proton-pump inhibitor that is commonly prescribed for the treatment of gastroesophageal reflux-related disorders. Acute interstitial nephritis is an uncommon though important side-effect of these classes of drugs. We reported a case with acute interstitial nephritis due to pantoprazole. A 25-year-old woman from Ardabil was admitted to our hospital with the complaint of fever, ...

2015
Markus Prause Claudine Seeliger Marina Unger Elizabeth Rosado Balmayor Martijn van Griensven Alexander Tobias Haug

Proton pump inhibitors (PPIs) are commonly prescribed drugs that decrease stomach acidity and are thus often used to treat gastroesophageal reflux disease and as a preventative agent for the adverse effects of nonsteroidal anti-inflammatory drugs on the stomach mucosa. In recently published literature, an association between proton pump inhibitor administration and increased fracture risk has b...

Journal: :molecular biology research communications 2014
mohsen jam abbas alemzadeh ali mohammad tale sara esmaeili-tazangi

the present study was conducted to find the effect of three heavy metals, ag, hg and pb on the expression level of a gene encoding plasma membrane h+-atpase in aeluropus littoralis. the experiment was laid out in a completely random design with three replications. the expression of the main gene was normalized to the expression of the housekeeping gene actin. two 259 and 187 bp fragments were a...

Journal: :The Annals of pharmacotherapy 2000
S Natsch M H Vinks A K Voogt E B Mees R H Meyboom

OBJECTIVE To report two cases of anaphylactic reactions to proton-pump inhibitors (PPIs). CASE SUMMARIES A 54-year-old woman who had taken omeprazole in the past was treated with omeprazole 40 mg and developed periorbital edema, edema of the skin, pruritus, nausea, and vomiting about 45 minutes after taking one capsule. Five months later, she was treated with lansoprazole 30-mg capsules. Agai...

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