78-[2-(2-Aminothiazol-4-yl)acetamido]-7a-methoxycephalosporins were synthesized both by acylation of the 7(3-amino-7a-methoxycephalosporin compound (VIII) and a new direct acyl-exchange reaction of 7a-methoxy-7,9-phosphoramido compound (VII). Some of these compounds (IXa, IXb) showed higher antibacterial activity than the 7a-unsubstituted compound against P-lactamase-producing strains of Serrat...

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Twenty strains of Proteus penneri obtained from the Centers for Disease Control, Atlanta, Ga., were tested for their ability to hemolyze sheep and human erythrocytes, a property that is thought to be connected with the invasiveness and virulence of Proteus species. In the logarithmic phase of growth, P. penneri cultures are hemolytic for such erythrocytes. This ability is comparable to the hemo...

The so-called Proteus-Providencia group is constituted at present by three genera and 10 species. Several of the recognized species are common opportunistic pathogens for humans and animals. Different methods based on the study of phenotypic characters have been used in the past with variable levels of efficiency for typing some species for epidemiological purposes. We have determined the rRNA ...