The carboxysome is a giant protein complex that acts as a metabolic organelle in cyanobacteria and some chemoautotrophs. Its outer structure is formed by the assembly of thousands of copies of hexameric shell protein subunits into a molecular layer. The structure determination of a CcmK1 shell protein mutant (L11K) from the β-carboxysome of the cyanobacterium Synechocystis PCC6803 led to challe...

Special libraries all over the world today fulfil a whole variety of different services at a wide range of locations. This diversified spectrum of activities is by no means a recent development. At the time that the Special Library Association (SLA) was founded at the 1909 conference of the American Library Association (ALA), special libraries already had little to do with traditional library t...

To investigate the interaction and adsorption of drug and carbon nanotube on human serum albumin, three anti-cancer drugs ([Pd(phen)(R-gly)]NO3, R = methyl, propyl and amyl) with different hydrophobic tails and anticancer activities were selected. These drugs have better anti-tumor activity and less side effects than that known cis-platinum drug. Human serum albumin is also ...

MOTIVATION Molecular Surface Patches (MSPs) of proteins are responsible for selective interactions between internal parts of one protein molecule or between protein and other molecules. The prediction of the neighbours of a distinct Secondary Structural Element (SSE) would be an important step for protein structure prediction. RESULTS Based on a computational analysis of complementary molecul...

Human serum albumin (HSA) is an abundant, multifunctional and nonglycosylated negatively charged plasma protein. HSA ascribed ligand-binding and transport properties, antioxidant functions and enzymatic activities. In the present study, the interaction and side effects of a new designed anti-cancer compound (1,10-phenanthroline butyl dithiocarbamato palladium(II) nitrate) on HSA have been inves...