نتایج جستجو برای: protein interaction map
تعداد نتایج: 1870650 فیلتر نتایج به سال:
Abstract Objective Retinoschisis and Norrie disease are X-linked recessive retinal disorders caused by mutations in RS1 NDP genes respectively. Both likely to be monogenic no locus heterogeneity has been reported. However, there reports showing overlapping features of retinoschisis a knock-out mouse model also the involvement both patients. Yet, exact molecular relationships between two have st...
In previous work we have demonstrated that the microtubule-associated protein 2 (MAP 2) molecule consists of two structural parts. One part of the molecule, referred to as the assembly-promoting domain, binds to the microtubule surface and is responsible for promoting microtubule assembly; the other represents a filamentous projection observed on the microtubule surface that may be involved in ...
The eukaryotic initiation factor 3 (eIF3) plays an important role in translation initiation, acting as a docking site for several eIFs that assemble on the 40S ribosomal subunit. Here, we use mass spectrometry to probe the subunit interactions within the human eIF3 complex. Our results show that the 13-subunit complex can be maintained intact in the gas phase, enabling us to establish unambiguo...
mountainous rangeland ecosystems have a highly delicate position in ecologic areabecause of severe environmental conditions and having wildlife and livestock. knowing andrealizing the biotic and abiotic components, which have an interaction with each other in thisecosystem, perform the most important role in to desirable management of it. the systematicmanagement is one of the managing features...
One of the most important factors for economic losses as result of infection with Mycobacterium avium ssp. paratuberculosis (MAP) is the decrease in milk yield. Different phenotyping methods for MAP lead to an inconsistent impact of MAP infection on milk parameters. It was the aim of the study to analyse the effect of the MAP status on milk yield, milk fat and milk protein (in kilograms), as we...
The biological response to tumor necrosis factor (TNF) involves activation of MAP kinases. Here we report a mechanism of MAP kinase activation by TNF that is mediated by the Rho GTPase family members Rac/Cdc42. This signaling pathway requires Src-dependent activation of the guanosine nucleotide exchange factor Vav, activation of Rac/Cdc42, and the engagement of the Rac/Cdc42 interaction site (C...
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