the anti-cancer activity of metal ions in the lanthanide group is being considered recently. it has been reported that cerium salts might stimulate the metabolism and therefore, produce anti-cancer effects. however, little is known about the effects of protein-cerium complex in controlling cancer cell growth. the aim of the present study was to elucidate the possible pathways for the cytotoxic ...

introduction and aims: helicobacter pylori commonly is associated with gastritis: but only sometimes it causes clinically significant diseases such as gastric and duodenal ulcer. the development of disease depends on the virulence of the infecting h. pylori strain, the susceptibility of the host, and environment co-factors. the cytotoxin associated protein encoded by caga gene is an important v...

although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure duration remain remains to be determined. in the present study, we examined the role of nmda (n-methyl-d-aspartate), non-nmda and estrogenic receptors in estradiol benzoate ...

Abstract Our objectives were to determine changes in colostrum yield and composition across the 36 hours post-calving effects of late gestational nutrient restriction (NR) on these changes. Fall-calving, crossbred beef heifers (BW: 472 ± 33 [SD] kg; BCS: 5.4 0.5) individually fed 100% (control; CON; n = 13) or 70% (NR; NASEM metabolizable energy protein requirements for maintenance, growth, pre...

background: the protein hormone granulocyte colony-stimulating factor (gcsf) stimulates the production of white blood cells and plays an important role in medical treatment of cancer patients. methods: an efficient process was developed for heterologous expression of human gcsf in e. coli bl21 (de3). the feeding rate was adjusted to achieve the maximum attainable specific growth rate under crit...

Clinically healthy adult black Bengal female goats were used to investigate the pharmacokinetics of closantel following intravenous administration (10 mg/kg) both in healthy and in liver damaged goats. Induction of liver damage was done by subcutaneous injection of carbontetrachloride at 0.75 mL/kg on three occasion at 48 h interval. After administration of drug, blood samples were collected in...

The pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (IV) and intramuscular (IM) administration at a dose rate of 10 mg/kg body weight. Ceftazidime concentrations in plasma and urine were determined by microbiological assay. Ceftazidime disposition was best fitted by a two-compartmental and a one-compar...