October 2006 | Volume 3 | Issue 10 | e394 The concept of health promotion gradually emerged from the discipline of public health during the 1970s. In the mid-19th century, founders of the growing discipline of public health had stressed the importance of social, political, and environmental factors as key determinants of disease and health. However, as microbiology and epidemiology developed, a...

We suggest a cure-mixture model to analyze bivariate time-to-event data, as motivated by the article of Chatterjee and Shih (2001, Biometrics 57, 779-786), but with a simpler estimation procedure and the correlated gamma-frailty model instead of the shared gamma-frailty model. This approach allows us to deal with left-truncated and right-censored lifetime data, and accounts for heterogeneity, a...

We propose a class of Bayesian cure rate models by incorporating a baseline density function as well as multiplicative and additive covariate structures. Our model naturally accommodates zero and non-zero cure rates, which provides an objective way to examine the existence of a survival fraction in the failure time data. An inherent parameter constraint needs to be incorporated into the model f...

This study examines the effectiveness of price versus nonprice promotion programs for U.S. poultry exports. A comparative static simulation framework is specified for this purpose. The elasticities needed for the simulation model are estimated using seemingly unrelated regression and time-varying parameter regression techniques. Results from this study indicate that a price subsidy is more effe...

Liver failure and liver diseases are major health problems worldwide leading to high mortality and also one of the high healthcare costs. Millions of patients die due to liver pathologies and liver diseases every year throughout the world. Use of stem cells to cure liver diseases has been proved beneficial in most of the conditions. Scientific literature reveals the role of stem cells in treatm...

This paper presents a framework for estimating losses for residential mortgage loans. At the core is a transitions-based probability of default model which yields directly observable cash-flows at the loan level. The estimated model includes coefficients on unemployment, Loan to Value ratio and interest rates, all of which allow a macroeconomic scenario to be fed through the model and impact lo...

In Back to First Principles: A New Model for the Regulation of Drug Promotion, Alan Bennett and co-authors rightly argue that it is time for the U.S. Food and Drug Administration (FDA) to reconsider its scheme for regulating prescription drug promotion.1 Bennett and his co-authors assert that the FDA’s framework for overseeing prescriptiondrug promotion is outdated because itwas developedover 5...

introduction: in the present study, the effects of light cure on wound healing of mice’s skin with complete thickness were studied. materials and methods: forty male mice of nmri race were placed randomly into two groups of examination and control. under aseptic and unconscious conditions, a circular wound of 6 mm width with complete thickness of skin was made on the back of each mice. the surg...