AIM To study the survival and visual outcome of penetrating keratoplasty in an African setting. METHODS A retrospective analysis of 216 corneal grafts, performed on 203 eyes of 186 patients, at Kikuyu Hospital, Kenya over a 5 year period. RESULTS Half of the transplants were carried out for keratoconus with only 5% of the grafts being undertaken for corneal scarring caused by trachoma or me...

PURPOSE To validate the estimation of corneal aberrations from videokeratography against a laser ray tracing technique that measured total eye aberrations, in eyes without keratoconus (ie, cornea-dominated wave aberrations). METHODS We measured total and corneal wave aberrations of three eyes diagnosed with keratoconus by slit-lamp microscopy and corneal topography: two eyes from one patient ...

PURPOSE To differentiate between keratoconus and contact lens-related corneal warpage by combining focal change patterns in anterior corneal topography, pachymetry, and epithelial thickness maps. METHODS Pachymetry and epithelial thickness maps of normal, keratoconus, and warpage, and forme fruste keratoconus (FFK) eyes were obtained from a Fourier-domain optical coherence tomography (OCT). E...

We report a familial case of keratoconus with corneal granular dystrophy. The mother and first son have both keratoconus and corneal granular dystrophy and the second son has keratoconus alone. The keratoconus in this family is thought to be an autosomal dominant or an X-linked inheritance pattern. Granular dystrophy is an autosomal dominant inheritance. This familial case suggests that the gen...

Objectives Comparison of topography and corneal higher order aberrations (HOA) data of fellow normal eyes of unilateral keratoconus patients with keratoconus eyes and control group. Materials and Methods The records of 196 patients with keratoconus were reviewed. Twenty patients were identified as unilateral keratoconus. The best corrected visual acuity (BCVA), topography and aberration data ...

Introduction: There are many reports on the association of various psychiatric disorders with visual impairment. The dry eye syndrome depressive has been particularly well documented. In context keratoconus patients group, data similar relationships inconclusive. Attempts have also made to assess personality suffering from keratoconus, and first study in this area was produced as early 1976. Ma...

Keratoconus (KC) is a progressive non-inflammatory ectatic corneal disease typified by thinning and conical protrusion, as well irregular astigmatism with varying-degree visual impairment. A literature review on the epidemiology, classification diagnosis presented. Current clinical practice most commonly relies Krumeich’s adaptation of ABCD grading system M. Belin Amsler. The KC requires compre...

Keratoconus (KC; OMIM 148300), the most common corneal dystrophy, is a bilateral, noninflammatory progressive corneal ectasia. Clinically, the cornea becomes progressively thin and conical which leads to myopia, irregular astigmatism, and corneal scarring. The transparency and refractive state of the cornea is a prerequisite for normal vision. The disease usually arises in the teenage years, ev...

BACKGROUND Keratoconus is a noninflammatory disease characterized by thinning and scarring of the central portion of the cornea. The etiology is unclear. In this study, we sought to identify mRNAs that are differentially expressed in the stroma of keratoconus corneas in comparison to those of corneas from normal individuals and patients with other corneal diseases. MATERIALS AND METHODS Total...

PURPOSE To report a corneal collagen cross-linking (CXL) mushroom shape demarcation line profile after limited Bowman's membrane removal by phototherapeutic keratectomy (PTK). METHODS Case report. RESULTS A twenty-one-year-old male with progressive keratoconus underwent mechanical epithelial debridement (at an 8.5 mm zone) followed by PTK (at a 5.0 mm zone and in a 10 μm depth) and CXL. No ...