This review touches on new insights into the possible role of Vitamin D receptors genetic polymorphisms, and steroid in patients diagnosed with breast cancer. is most common cancer women; further, it creates diverse illnesses among diseased patients, prognosis linked different subtypes present hormone receptors. Most studies focus epidemiology disease. However, fewer are done genes polymorphism...

psa is a 33-kda serine protease that is produced predominantly by prostate epithelium. however, it has been shown that about 30-40% of female breast tumors produce psa and its production is associated with the presence of estrogen and progesterone receptors. we have now developed a new tissue culture system to study psa production in breast cancer and its association with prognostic factors suc...

K E Y W O R D S breast cancer, estrogen and progesterone receptors, cytochemistry, fluorescence

Aim: Estrogens and progesterone are essential for breast development in women. Paradoxically they promote the of cancer, through stimulation proliferation cells by action hormone receptors. In Côte d'Ivoire, more than half all diagnosed cases cancer hormone-dependent. Because link between female hormones consideration certain factors, such as period influence (estrogen progesterone) well their ...

Traditionally, steroid receptors were believed to be activated only by ligand binding; however, recent studies indicate that steroid receptors can also be activated by mechanisms that do not require ligand, referred to as ligand-independent activation. Specifically, progestin receptors can be activated in vitro and in vivo after treatment with neurotransmitters, such as dopamine, in the absence...

The qualitative and quantitative relationships between cytoplasmic estrogen receptors (ERC), total nuclear estrogen receptors (ERN), and cytoplasmic progesterone receptors (PGR) in 74 primary and 23 metastatic human breast cancer tissues were studied. A positive correlation between the age of th patients and the receptor concentration was found only for ERC. Although ERN and PGR were more frequ...

Objective(s): Neuroprotective effects of female gonadal steroids are mediated through several pathways involving multiple peptides and receptors after traumatic brain injury (TBI). Two of these peptides are including the regulatory peptides neuromedin U (NMU) and neuromedin S (NMS), and their common receptor neuromedin U2 receptor (NMUR2). This study investigates the effects of physiological do...