نتایج جستجو برای: primary antibody deficiencies
تعداد نتایج: 814713 فیلتر نتایج به سال:
coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with immunodeficiencies has been reported previously in patients who suffered from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...
a common cause for community acquired pneumonia, but recurrent infections are unusual in a young, healthy non-smoker. Thus repeated infections with these organisms should prompt investigations for possible underlying immunodeficiency. When evaluating patients with recurrent infection, use the acronym SPUR (severe, persistent, unusual, or recurrent) to prompt appropriate investigations for under...
Background and Objective: Rh (Rhesus) is a highly complex blood group system in man which plays an important role in transfusion medicine. The aim of this study was the isolation of RhD protein from the membrane of RBCs. Materials and Methods: In this experimental study immunoprecipitation method with human anti-RhD polyclonal antibody was utilized for the isolation of RhD antigen from Rh+ huma...
Intravenous immunoglobulin administered at replacement dosages modulates innate and adaptive immune cells in primary antibody deficiencies (PAD) in a different manner to what observed when high dosages are used or when their effect is analyzed by in vitro experimental conditions. The effects seem to be beneficial on innate cells in that dendritic cells maturate, pro-inflammatory monocytes decre...
Immunoglobulin class-switch recombination deficiencies (Ig-CSR-Ds) are rare primary immunodeficiencies characterized by defective switched isotype (IgG/IgA/IgE) production. Depending on the molecular defect in question, the Ig-CSR-D may be combined with an impairment in somatic hypermutation (SHM). Some of the mechanisms underlying Ig-CSR and SHM have been described by studying natural mutants ...
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