Combination antiretroviral therapy reduces overall and liver-specific morbidity and mortality in coinfection with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) and represents the most beneficial pharmaceutical treatment intervention for most coinfected patients. Antiviral therapy for HCV infection is potentially organ- and life-saving but, in general, should be reserved for pat...

Antimalarial chemotherapy, globally reliant on artemisinin-based combination therapies (ACTs), is threatened by the spread of drug resistance in Plasmodium falciparum parasites. Here we use zinc-finger nucleases to genetically modify the multidrug resistance-1 transporter PfMDR1 at amino acids 86 and 184, and demonstrate that the widely prevalent N86Y mutation augments resistance to the ACT par...

signs and symptoms of d ph toxicity were seen in an epileptic child who had received dph and mp concurrently. in the absence of liver and kidney disease and any intercurrent infection, and with the patient's recovery following the withdrawal of dph, it appears that drug-drug interaction is the most logical explanation for dph intoxication.

Cells too get ambiguous - JOOO- Print ISSN No: 2395-6186 Online No:- 2395-6194 Article DOI 10.18231/j.jooo.2023.001, Journal of Oral Medicine, Surgery, Pathology and Radiology-J Med Surg Pathol Radiol

Cover Page Footnote: This paper was given as Invited Lecture at ICA 1994. It was published in 1995 in Threatened Peoples and Environments in the Americas, Proceedings of the 48th International Congress of Americanists, M. Marner and M. Rosendahl (eds), pp. 39-49, Stockholm: Institute of Latin American Studies. Not only is this publication out of print and very difficult to find, but the theme o...

We study a persuasion game à la Kamenica and Gentzkow (2011) where players are ambiguity averse with maxmin expected utility (Gilboa and Schmeidler, 1989). With no prior ambiguity, Sender might choose to use ambiguous communication devices. The main result characterizes the value of optimal ambiguous persuasion, which is often higher than what is feasible under Bayesian persuasion. We character...