current guidelines suggest that the ppd mantoux tuberculin test should be read after 48 or 72 hours. we have compared the measurements at these time points. a 5-tuberculin unit (tu) ppd mantoux test was administered to 100 subjects (91% with bacillus calmette- guerin scars). induration was measured 48 and 72 hours following the injection. results the measurements made at 72nd hour were signific...

PURPOSE Diagnosis of tuberculosis (TB) in children is more challenging than in adults. This study aimed to describe demographical, clinical and laboratory findings of children diagnosed with tuberculosis in Turkey, including the issues of contact tracing, culture positivity and forms of the disease. MATERIALS AND METHODS Clinical and laboratory data of 51 children with a mean age of 8.0±4.6 y...

Persons whose reaction to tuberculin has changed from negative to positive are known as tuberculin converters. There is widespread interest in chemotherapy for tuberculin converters as a means of preventing the development of clinical tuberculosis. Drug therapy of this kind is referred to as chemoprophylaxis. The effectiveness of chemoprophylaxis is thought to be greatest when offered to those ...

BACKGROUND Health care workers are exposed to patients with tuberculosis and are at risk of nosocomial infection. The aim of this study was to determine the prevalence and factors associated with latent tuberculosis infection among health care workers in Malaysia and also to evaluate the agreement between Quantiferon TB Gold in tube test with Tuberculin Skin Test. METHODS A cross sectional st...

CONTEXT Budgetary constraints in tuberculosis (TB) control programs require streamlining contact investigations without sacrificing disease control. OBJECTIVE To develop more efficient methods of TB contact investigation by creating a model of TB transmission using variables that best predict a positive tuberculin skin test among contacts of an active TB case. DESIGN, SETTING, AND SUBJECTS ...

The Medical Research Council's trial of BCG and vole bacillus vaccines in the prevention of tuberculosis in Great Britain has ended after 20 years' follow-up of the 54 239 participants, who were aged 14 to 15 years when the entered the trial in 1950-2. Participants who were tuberculin positive on entry were left unvaccinated; those who were tuberculin negative were allocated at random to an unv...

SETTING Health care workers (HCWs) are at increased risk for tuberculosis (TB) infection. In China, surveys examining TB infection among HCWs have not studied general health care facilities, compared tuberculin tests conducted using local protocols against an internationally accepted test or characterised risk factors. OBJECTIVE To measure the prevalence of and risk factors for TB infection ...

BACKGROUND Healthcare workers in high tuberculosis burdened countries are occupationally exposed to the tuberculosis disease with uncomplicated and complicated tuberculosis on the increase among them. Most of them acquire Mycobacterium tuberculosis but do not progress to the active disease - latent tuberculosis infection. The objective of this study was to assess the prevalence and risk factors...